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个人简介
Working in close collaboration with the radiochemistry laboratory of Dr. Victor Pike, my laboratory uses in vivo imaging to evaluate novel positron emission tomographic (PET) radioligands, first in animals, then in healthy human subjects, and finally in patients. My laboratory has multidisciplinary expertise in pharmacology, animal experimentation, clinical neuroscience, digital image analysis, and human evaluation of investigational radiopharmaceuticals. In addition to traditional receptor targets, we use radiolabeled probes for in vivo imaging of neuroinflammation (including translocator protein, COX-1, and COX-2) and intracellular signal transduction (eg, cAMP phosphodiesterase). A major goal of the lab is to use these radioligands to facilitate clinical trials of novel therapeutics. Such trials are in the early planning stages with regard to phosphodiesterase-4 (PDE4) and neuroinflammation in depression.
研究兴趣
论文共 769 篇作者统计合作学者相似作者
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Mia Scrabis,Nafiseh Ghazanfari, Paul Parcon,Jeih-San Liow, Raven Cureton, Carson Knoer,Madeline Jenkins, Andrew Mannes,Jinsoo Hong, Fatemeh Ahmadi, Jose Montero Santamaria,Umesha Shetty,
Matilah Pamie-George,Meijuan Jiang,Shiyu Tang,Madeline Jenkins,Adrian Lee, Bruny Kenou, Carson Knoer, Jose Montero Santamaria,Shawn Wu,Jeih-San Liow,Sami Zoghbi,Robert Innis,
Amanda Bardhoshi, Paul Parcon,Jeih-San Liow, Amanda Olsen-Dufour,Shawn Wu,Cheryl Morse,Victor Pike,Robert Innis
Raven Cureton, Mudasir Maqbool,Daniel Gündel,Jeih-San Liow,Shawn Wu,Jinsoo Hong,Victor Pike,Robert Innis
Biological Psychiatryno. 10 (2024): S158-S159
Adrian Lee, Sridhar Goud Nerella,Sanjay Telu,Jeih-San Liow,Madeline Jenkins,Sami Zoghbi,Robert Innis,Victor Pike,Mark Eldridge, Michael Michaelides
Amanda Bardhoshi, Paul Parcon,Jeih-San Liow, Amanda Olsen-Dufour,Shawn Wu,Cheryl Morse,Victor Pike,Robert Innis
Biological Psychiatryno. 9 (2023): S110-S110
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European journal of nuclear medicine and molecular imagingno. 10 (2023): 2962-2970
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