基本信息
浏览量:3
职业迁徙
个人简介
My long-term research interests center on understanding the molecular mechanisms of viral-host interactions and the application of this information to develop new antiviral strategies. We have used mass spectrometry technologies to identify cellular factors that interact with Hepatitis C virus through a collaboration with Dr. Nevan Krogan. We comprehensively characterized HCV-host protein-protein interactions, and tested the functional requirements of these interactions using an RNAi screen. This led to the identification of 69 new host factors that physically interact with HCV and influence infection. This wealth of data serves as a platform for as I continue my work at the University of Pennsylvania. We are particularly interested in host factors that are involved in infection with related viruses and have generated a West Nile virus-host protein-protein interaction dataset to make these comparisons.
研究兴趣
论文共 23 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Marcus J. Bolton,Jefferson J. S. Santos,Claudia P. Arevalo,Trevor Griesman, Megan Watson, Shuk Hang Li,Paul Bates,Holly Ramage,Patrick C. Wilson,Scott E. Hensley
bioRxiv : the preprint server for biology (2023)
引用0浏览0WOS引用
0
0
medRxiv : the preprint server for health sciences (2021)
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn