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Our research aims to complement the highly developed genomics and proteomics of Caenorhabditis elegans, one of the most important biomedical model organisms, with a comprehensive structural and functional annotation of its metabolome: a vast universe of >10,000 different small molecules, most of which have not been chemically identified or biologically characterized. The analytical tools we develop to identify structures and functions of biogenic small molecules will be transferable to other animal models, setting the stage for a functional annotation of mammalian metabolomes. In addition we have started a project directed at investigating the chemical ecology of microorganisms in search of leads for new antibiotics. Complementing our interests in analytical chemistry, biosynthesis, and small-molecule signaling, we pursue development of efficient syntheses for newly identified compounds and derivatives for receptor identification via click chemistry approaches.
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论文共 322 篇作者统计合作学者相似作者
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Cell Reportsno. 4 (2024): 113996-113996
Akshita Kamboj, Jennifer Thielmann,Saba Delfan, Tim Kloppe, Philipp Schulz,Murli Manohar,Frank C. Schroeder,Daniel F. Klessig, Karl-Heinz Kogel
crossref(2024)
Mark G Zhang,Maedeh Seyedolmohadesin, Soraya Hawk,Heenam Park, Nerissa Finnen,Frank Schroeder,Vivek Venkatachalam,Paul W Sternberg
bioRxiv : the preprint server for biology (2024)
Agata Szczepanska, Katarzyna Olek, Klaudia Kolodziejska, Jingfang Yu, Abdulrahman Tudu Ibrahim, Laura Adamkiewicz,Frank C. Schroeder, Wojciech Pokrzywa,Michal Turek
NATURE COMMUNICATIONSno. 1 (2024): 2715-2715
Chih-Yen Kuo, Rebecca J. Tay, Hung-Che Lin, Sheng-Chian Juan, Guillermo Vidal-Diez de Ulzurrun,Yu-Chu Chang, Jason Hoki,Frank C. Schroeder,Yen-Ping Hsueh
Woo Kyu Kang,Jeremy T. Florman, Antonia Araya,Bennett W. Fox,Andrea Thackeray,Frank C. Schroeder, Albertha J. M. Walhout,Mark J. Alkema
NATURE CELL BIOLOGYno. 1 (2024): 72-85
Mateusz Maciej Wagner, Jieun Kang, Catherine Mercado, Venkatesh P Thirumlaikumar, Michal Gorka, Hanne Zillmer, Jingze Guo,Romina I Minen, Caroline F Plecki, Katayoon Dehesh,Frank C Schroeder, Dirk Walther,
biorxiv(2024)
Proceedings of the National Academy of Sciences of the United States of Americano. 5 (2024): e2307515121-e2307515121
Bennett W. Fox,Maximilian J. Helf,Russell N. Burkhardt, Alexander B. Artyukhin,Brian J. Curtis, Diana Fajardo Palomino, Allen F. Schroeder,Amaresh Chaturbedi, Arnaud Tauffenberger,Chester J. J. Wrobel,Ying K. Zhang,Siu Sylvia Lee,
Nature Communicationsno. 1 (2024): 1-15
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