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Dr. Klein is a Professor of Oncology, Pathology and Epidemiology and a trained genetic epidemiologist/statistical geneticist. She has studied the genetic epidemiology of pancreatic cancer for over 17 years. Her research has focused on the discovery of pancreatic cancer susceptibility genes, using linkage, sequencing and association approaches as well as quantification of pancreatic cancer risk due to familial and genetic factors. As part of this work, she has identified rare variants in PALB2 and ATM are associated with familial pancreatic cancer, as well as lead the Pancreatic Cancer Case Control Consortium Genome-Wide association studies of pancreatic cancer (NCI RO1/CIDR supported).
Dr. Klein is Director of the National Familial Pancreas Tumor Registry, the largest single-site registry of familial pancreatic cancer in the world. Currently, over 6,500 families have enrolled in this registry including over 1,700 with familial pancreatic cancer (i.e., defined as a kindred with at least a pair of first-degree relatives with pancreatic cancer). In addition, she is co-leader of the Familial Pancreatic Cancer Genome Sequencing Project conducted within the PACGENE consortium where we have recently completed whole genome sequencing analysis of 638 patients with familial pancreatic cancer. She is also the PI of a NCI/CIDR supported multi-center GWAS for pancreatic cancer and PI of the Johns Hopkins SPORE in Gastrointestinal cancer. She is a founding member of the Pancreatic Cancer Case-Control Consortium and member of the SU2C Pancreatic Cancer Interception Dream Team.
Dr. Klein is Director of the National Familial Pancreas Tumor Registry, the largest single-site registry of familial pancreatic cancer in the world. Currently, over 6,500 families have enrolled in this registry including over 1,700 with familial pancreatic cancer (i.e., defined as a kindred with at least a pair of first-degree relatives with pancreatic cancer). In addition, she is co-leader of the Familial Pancreatic Cancer Genome Sequencing Project conducted within the PACGENE consortium where we have recently completed whole genome sequencing analysis of 638 patients with familial pancreatic cancer. She is also the PI of a NCI/CIDR supported multi-center GWAS for pancreatic cancer and PI of the Johns Hopkins SPORE in Gastrointestinal cancer. She is a founding member of the Pancreatic Cancer Case-Control Consortium and member of the SU2C Pancreatic Cancer Interception Dream Team.
Research Interests
Papers共 149 篇Author StatisticsCo-AuthorSimilar Experts
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Manal M. Hassan,Donghui Li,Younghun Han,Jinyoung Byun,Rikita I. Hatia,Erping Long,Jiyeon Choi,Robin Kate Kelley,Sean P. Cleary,Anna S. Lok,Paige Bracci,Jennifer B. Permuth,Roxana Bucur,Jian-Min Yuan,Amit G. Singal,Prasun K. Jalal,R. Mark Ghobrial,Regina M. Santella,Yuko Kono,Dimpy P. Shah,Mindie H. Nguyen,Geoffrey Liu,Neehar D. Parikh,Richard Kim,Hui-Chen Wu,Hashem El-Serag,Ping Chang, Yanan Li,Yun Shin Chun,Sunyoung S. Lee,Jian Gu,Ernest Hawk,Ryan Sun,Chad Huff,Asif Rashid,Hesham M. Amin,Laura Beretta,Robert A. Wolff,Samuel O. Antwi,Yehuda Patt,Lu-Yu Hwang,Alison P. Klein,Karen Zhang,Mikayla A. Schmidt,Donna L. White,John A. Goss,Saira A. Khaderi,Jorge A. Marrero,Francisco G. Cigarroa,Pankil K. Shah,Ahmed O. Kaseb,Lewis R. Roberts,Christopher I. Amos
Hepatology (2024)
Juan M. Lavista,Felipe Oviedo, Caleb Robinson,Linda Chu,Satomi Kawamoto,Elham Afghani,Jin He,Alison P. Klein, Mike Goggins,Christopher L. Wolfgang, Ammar A. Javed,Rahul Dodhia, Nick Papadopolous, Ken Kinzler,Ralph H. Hruban, William B. Weeks,Elliot K. Fishman, Anne Marie Lennon
Pancreatology (2024)
Zhanmo Ni,Prosenjit Kundu, David F McKean,William Wheeler,Demetrius Albanes,Gabriella Andreotti,Samuel O Antwi,Alan A Arslan,William R Bamlet,Laura E Beane-Freeman,Sonja I Berndt,Paige M Bracci,Paul Brennan,Julie E Buring,Stephen J Chanock,Steven Gallinger,J M Gaziano,Graham G Giles,Edward L Giovannucci,Michael G Goggins,Phyllis J Goodman,Christopher A Haiman,Manal M Hassan,Elizabeth A Holly,Rayjean J Hung,Verena Katzke,Charles Kooperberg,Peter Kraft,Loic LeMarchand,Donghui Li,Marjorie L McCullough,Roger L Milne,Steven C Moore,Rachel E Neale,Ann L Oberg,Alpa V Patel,Ulrike Peters,Kari G Rabe,Harvey A Risch,Xiao-Ou Shu,Karl Smith-Byrne,Kala Visvanathan,Jean Wactawski-Wende,Emily White,Brian M Wolpin,Herbert Yu,Anne Zeleniuch-Jacquotte,Wei Zheng,Jun Zhong,Laufey T Amundadottir, Rachael Z Stolzenberg-Solomon,Alison P Klein
Cancer epidemiology, biomarkers & prevention a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncologyno. 9 (2024): 1229-1239
Familial Cancerpp.1-10, (2024)
JCO PRECISION ONCOLOGY (2024)
Nicolette J. Rodriguez,C. Sloane Furniss,Matthew B. Yurgelun,Chinedu Ukaegbu,Pamela E. Constantinou,Ileana Fortes,Alyson Caruso,Alison N. Schwartz,Jill E. Stopfer,Meghan Underhill-Blazey,Barbara Kenner,Scott H. Nelson,Sydney Okumura,Alicia Y. Zhou,Tara B. Coffin,Hajime Uno,Miki Horiguchi,Allyson J. Ocean,Florencia McAllister,Andrew M. Lowy,Alison P. Klein,Lisa Madlensky,Gloria M. Petersen,Judy E. Garber,Scott M. Lippman,Michael G. Goggins, Anirban Maitra,Sapna Syngal
Gastroenterology (2024)
Minal B Patel, Aidan O'Brien,Jun Zhong,Irene Collins,Jason W Hoskins, Stephen J Chanock,Samuel O Antwi, Rachel Z Stolzenberg-Solomon,Alison P Klein,Brian M Wolpin,Sara Lindström,H. Efsun Arda, Kevin M Brown,Katelyn E Connelly,Laufey T Amundadottir, Meagan Jezek
Cancer Researchno. 17_Supplement_2 (2024)
Erica J. Childs,Kari G. Chaffee,Steven Gallinger,Sapna Syngal,Ann G. Schwartz,Michele L. Cote,Melissa L. Bondy, Ralph H. Hruban, Stephen J. Chanock,Robert N. Hoover,Charles S. Fuchs,David N. Rider,Laufey T. Amundadottir,Rachael Stolzenberg-Solomon,Brian M. Wolpin,Harvey A. Risch,Michael G. Goggins,Gloria M. Petersen,Alison P. Klein
crossref(2023)
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Author Statistics
#Papers: 147
#Citation: 20163
H-Index: 37
G-Index: 141
Sociability: 8
Diversity: 0
Activity: 3
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