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Doctor Kelsoe and his collaborators have long been interested in the biology of B lymphocytes and have worked to demonstrate stochastic variable (V) gene segment use in the primary B-cell repertoire; the migrations of antigen-activated T and B lymphocytes during humoral responses; the germinal center as the primary site of V(D)J hypermutation and affinity-driven selection; the role of complement in the germinal center response and affinity maturation of serum antibodies; the nature, role, and distribution of cryptic, V(D)J recombination signals in the mammalian genome; and the basic mechanisms of central B-cell tolerance.
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论文共 326 篇作者统计合作学者相似作者
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John Barber,Chen-Hao Yeh, Helene Kirshner,Kevin Saunders,Kevin Wiehe,Ming Tian,Frederick Alt,Barton Haynes,Garnett Kelsoe
Clinical Immunology (2024): 110058
Nature Reviews Immunologyno. 4 (2023): 265-265
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Joel Finney,Annie Park Moseman, Susan Kong,Akiko Watanabe, Shengli Song,Richard M. Walsh Jr,Masayuki Kuraoka,Ryutaro Kotaki,E. Ashley Moseman, Kevin R. Mccarthy,Dongmei Liao, Xiaoe Liang,
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICAno. 1 (2023): e2316964120-e2316964120
bioRxiv : the preprint server for biology (2023)
Holly C. Simmons,Akiko Watanabe, Thomas H. Oguin III, Elizabeth S. Van Itallie,Kevin J. Wiehe,Gregory D. Sempowski,Masayuki Kuraoka,Garnett Kelsoe,Kevin R. Mccarthy
PLOS BIOLOGYno. 12 (2023): e3002415-e3002415
NATURE REVIEWS IMMUNOLOGYno. 4 (2023): 265-265
bioRxiv (Cold Spring Harbor Laboratory) (2023)
NATURE REVIEWS IMMUNOLOGYno. 3 (2022): 142-158
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