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Dr Holmes has a key research focus on evaluating how cardiorespiratory reflex dysfunction caused by hyperactive carotid body chemoreceptors promotes hypertension and cardiac autonomic dysfunction. He aims to develop new or repurposed therapies that directly target the carotid body to reduce hypertension and arrhythmia in associated diseases such as obstructive sleep apnoea and COPD. This work is currently supported by the Wellcome Trust.
In addition, he has a specific interest in understanding how acute and chronic hypoxia disrupt the electrical integrity of atrial tissue leading to heart rhythm disturbances. This work is currently supported by grants from BHF.
In addition, he has a specific interest in understanding how acute and chronic hypoxia disrupt the electrical integrity of atrial tissue leading to heart rhythm disturbances. This work is currently supported by grants from BHF.
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论文共 81 篇作者统计合作学者相似作者
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Scientific Datano. 1 (2024): 93-93
Christopher O'Shea,James Winter,S. Nashitha Kabir, Molly O'Reilly,Simon P. Wells, Olivia Baines,Laura C. Sommerfeld,Joao Correia,Ming Lei,Paulus Kirchhof,Andrew P. Holmes,Larissa Fabritz,
SCIENTIFIC DATAno. 1 (2024)
Rina Sha, Olivia Baines, Abbie Hayes, Katie Tompkins,Manish Kalla,Andrew P. Holmes, Christopher O'Shea,Davor Pavlovic
JOURNAL OF THE AMERICAN HEART ASSOCIATIONno. 1 (2024): e032277-e032277
Laura C. Sommerfeld,Andrew P. Holmes,Ting Y. Yu, Christopher O'Shea,Deirdre M. Kavanagh,Jeremy M. Pike,Thomas Wright,Fahima Syeda, Areej Aljehani, Tania Kew, Victor R. Cardoso,S. Nashitha Kabir,
JOURNAL OF PHYSIOLOGY-LONDON (2024)
F1000Research (2024): 1224-1224
Chris Denning,Andrew P Holmes,Katja Gehmlich,Nguyen T N Vo,Paulus Kirchhof,Jonas Euchner,Amar J Azad, Max J Cumberland
F1000Research (2024)
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Ashwin Roy, Max J. Cumberland, Christopher O’Shea,Andrew Holmes,Manish Kalla,Katja Gehmlich,Tarekegn Geberhiwot,Richard P. Steeds
Current Cardiology Reportspp.1-16, (2024)
Olivia Baines, Rina Sha,Manish Kalla,Andrew P. Holmes,Igor R. Efimov,Davor Pavlovic, Christopher O'Shea
EUROPACEno. 2 (2024)
Cellsno. 12 (2023): 1661-1661
ARTERIAL CHEMORECEPTORS (2023): 175-184
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