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My research focuses on how memory is encoded in rodents at the molecular level, and how these molecular changes support the establishment and persistence of a memory. Even though we have known of the molecular basis of memory for over a decade, how the molecular events sum together to give rise to memory is still not understood. Currently I am focused on “transient” players in memory formation, focusing on mRNA itself. This view was spurred by the observation that the synapse is capable of local translation (IE within the synapse) of mRNA into proteins, giving synapses a vital role in local regulation of translation and thus how synapses respond to experience.
My research focuses on how memory is encoded in rodents at the molecular level, and how these molecular changes support the establishment and persistence of a memory. Even though we have known of the molecular basis of memory for over a decade, how the molecular events sum together to give rise to memory is still not understood. Currently I am focused on “transient” players in memory formation, focusing on mRNA itself. This view was spurred by the observation that the synapse is capable of local translation (IE within the synapse) of mRNA into proteins, giving synapses a vital role in local regulation of translation and thus how synapses respond to experience.
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Amanda M Leonetti, Isabella R Galluzzo, Timothy A D McLean,Gilda Stefanelli, Fiona Ramnaraign, Samuel Holm, Stephen M Winston, Isaiah L Reeves,Mark A Brimble,Brandon J Walters
Neurobiology of learning and memory (2024): 107903-107903
Cell reportsno. 7 (2021): 109551-109551
MOLECULAR-GENETIC AND STATISTICAL TECHNIQUES FOR BEHAVIORAL AND NEURAL RESEARCHpp.345-382, (2018)
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Klotilda Narkaj,Gilda Stefanelli,Malak Wahdan, Amber B Azam,Firyal Ramzan, Carl Frank David Steininger,Brandon J Walters,Iva B Zovkic
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