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We focus on the psychological mechanisms of antidepressant drug action with conventional and novel candidate treatments, challenging the typical division between these different approaches. To do this, we apply an experimental medicine approach, focused on neurocognitive measures of emotional processing in both healthy volunteers and patient samples.
This research helps to integrate psychological and pharmacological views of depression and treatment and has challenged the way in which we typically consider drug treatment for depression to work (see Harmer et al 2017). In addition this research has led to the development of human experimental models to explore the effects of novel drugs for the treatment of depression and anxiety. This work has also been applied in the clinic to provide an earlier marker of SSRI non-response in primary care (Browning et al., 2021).
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论文共 8 篇作者统计合作学者相似作者
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Tarek Zghoul, Pilar Artiach Hortelano,Alexander Kaltenboeck,Lucy Wright,Guy Goodwin,Liliana Capitao,Catherine Harmer
medrxiv(2023)
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medRxiv (Cold Spring Harbor Laboratory) (2023)
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Psychological medicineno. 13 (2023): 6389-6396
FRONTIERS IN PSYCHOLOGY (2023)
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