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Dr. Jamieson specialized in myeloproliferative disorders (MPDs) and leukemia. Myeloproliferative neoplasms are a family of uncommon but not rare degenerative disorders in which the body overproduces blood cells. Myeloproliferative neoplasms can cause many forms of blood clotting including heart attack, stroke, deep venous thrombosis, and pulmonary emboli and can develop into acute myelogenous leukemia. Although some effective treatments are available, they are laden with serious side effects. In addition, individuals can become resistant to the treatments. Dr. Jamieson studies the mutant stem cells and progenitor cells in myeloproliferative neoplasms. These cells can give rise to cancer stem cells. Cancer stem cells may lie low to evade chemotherapy and then activate again later, causing disease progression and resistance to treatment. Her goal is to find more selective, less toxic therapies. In the past two years, Dr. Jamieson’s stem-cell research studies have taken a great leap: from identifying a promising treatment in the laboratory to opening and completing the first clinical trial to target cancer stem cells in humans. This trial is the result of teamwork that has brought together her discoveries in myeloproliferative neoplasms and a local pharmaceutical company’s drug development track.
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Cancer Researchno. 6_Supplement (2024): 2767-2767
Gregory P Botta,Joseph Chao, Hong Ma, Michael Hahn, Gloria Sierra,Jie Jia,Amanda Y Hendrix, Joy V Nolte Fong, Audrey Ween,Peter Vu,Aaron Miller,Michael Choi,
Journal for immunotherapy of cancerno. 2 (2024)
Jessica Pham,Jane Isquith,Larisa Balaian,Luisa Ladel, Shuvro P. Nandi, Karla Mack,Inge van der Werf, Emma Klacking, Antonio Ruiz, David Mays, Paul Gamble, Shelby Giza,
biorxiv(2024)
Maria Rivera,Haoran Zhang,Jessica Pham,Jane Isquith, Qingchen Jenny Zhou,Larisa Balaian,Roman Sasik, Sabina Enlund,Adam Mark,Wenxue Ma,Frida Holm,Kathleen M. Fisch,
Maria Dolores Rivera,Haoran Zhang, Qingchen Zhou,Jessica Pham,Jane Isquith,Roman Sasik,Adam Mark, Sabina Enlund,Frida Holm,Ma Wenxue, Kathleen Fisch, Dennis Kuo,
Cancer Researchno. 6_Supplement (2024): 5448-5448
Rebecca A. Shatsky, Hemali Batra-Sharma,Teresa Helsten,Richard B. Schwab,Emily I. Pittman,Minya Pu,Elizabeth Weihe,Emanuela M. Ghia,Laura Z. Rassenti,Alfredo Molinolo, Betty Cabrera,James B. Breitmeyer,
Inge van der Werf,Larisa Balaian,Jessica Pham,Wenxue Ma, Athena Mohebbi, Emma Klacking, Antonio Ruiz, Karla Mack, John Mascarenhas,Thomas Whisenant,Ludmil Alexandrov,Sheldon Morris,
Cancer Researchno. 6_Supplement (2024): 263-263
The New England journal of medicineno. 14 (2023): 1310-1319
Cell reports. Medicineno. 3 (2023): 100962-100962
CANCER RESEARCHno. 7 (2023)
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