基本信息
浏览量:22
职业迁徙
个人简介
Research interests
Dr Jackson’s research team is directly involved with several departments at Royal North Shore Hospital including Rheumatology, the Severe Burns Unit, Dermatology, Endocrinology and the Institute of Bone and Joint Research at the University of Sydney. Dr Jackson works closely with the clinicians and co-supervises PhD students from those departments. These strong links ensure that human specimens are readily available for his research. Additionally, they ensure that his research is patient-orientated with the ultimate aim of solving health issues related to arthritis, particularly rheumatoid arthritis, and inflammatory skin conditions.
The strategies used for Dr Jackson’s research has allowed it to become true bench to bedside translational research. After making the original discovery that activated protein C (APC) heals wounds, Dr Jackson was given the opportunity to develop the concept with an NHMRC Development Grant (#25388, Activated protein C to promote wound healing, 2003-5). Together with Dr Meilang Xue, he undertook extensive basic laboratory studies, including pre-clinical animal studies to obtain proof-of-concept. With help from his clinical colleagues at RNSH, he progressed the work to pilot human clinical trials in diabetic chronic wounds. With clinical collaborations firmly established and positive results from pilot studies showing that APC has strong potential to heal human chronic wounds, A randomised double-blind controlled clinical trial will shortly begin to test the efficacy of an APC variant to treat diabetic chronic leg ulcers, funded by NHMRC 1032549 grant and commercial sponsorship.
Dr Jackson’s research team is directly involved with several departments at Royal North Shore Hospital including Rheumatology, the Severe Burns Unit, Dermatology, Endocrinology and the Institute of Bone and Joint Research at the University of Sydney. Dr Jackson works closely with the clinicians and co-supervises PhD students from those departments. These strong links ensure that human specimens are readily available for his research. Additionally, they ensure that his research is patient-orientated with the ultimate aim of solving health issues related to arthritis, particularly rheumatoid arthritis, and inflammatory skin conditions.
The strategies used for Dr Jackson’s research has allowed it to become true bench to bedside translational research. After making the original discovery that activated protein C (APC) heals wounds, Dr Jackson was given the opportunity to develop the concept with an NHMRC Development Grant (#25388, Activated protein C to promote wound healing, 2003-5). Together with Dr Meilang Xue, he undertook extensive basic laboratory studies, including pre-clinical animal studies to obtain proof-of-concept. With help from his clinical colleagues at RNSH, he progressed the work to pilot human clinical trials in diabetic chronic wounds. With clinical collaborations firmly established and positive results from pilot studies showing that APC has strong potential to heal human chronic wounds, A randomised double-blind controlled clinical trial will shortly begin to test the efficacy of an APC variant to treat diabetic chronic leg ulcers, funded by NHMRC 1032549 grant and commercial sponsorship.
研究兴趣
论文共 151 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
RHEUMATOLOGYno. 2 (2024): 571-580
Christopher T Jackson,Jeffrey W Wang,Eduardo González-Grandío,Natalie S Goh,Jaewan Mun,Sejal Krishnan, Florian Ludwig Geyer,Harald Keller,Sophia Ebert,Kian Molawi, Nadine Kaiser,Markita P Landry
Ruilong Zhao, Duo Wang, Thomas Charles Lang,Albert Kim,Aruna Wijewardana,John Vandervord,Rachel McGrath,Gregory Fulcher,Haiyan Lin,Meilang Xue,Christopher John Jackson
European Burn Journalno. 4 (2021): 226-237
Fernando Pereira Beserra,Lucas Fernando Sérgio Gushiken, Maria Fernanda Hussni,Victor Pena Ribeiro, Flávia Bonamin,Christopher John Jackson,Cláudia Helena Pellizzon,Jairo Kenupp Bastos
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn