基本信息
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个人简介
Specialty Areas
Host Defense Mechanisms in the Lungs, Bacterial Pneumonia, Acute Lung Injury/Acute Respiratory Distress Syndrome, Cigarette- Induced Lung Disease
Research Focus
Dr. Doerschuk’s research addresses host defense mechanisms in the lungs, particularly the inflammatory and innate immune processes that are important in the pathogenesis and course of bacterial pneumonia, acute lung injury/acute respiratory distress syndrome, and cigarette-smoke induced lung disease. Basic and translational studies address the mechanisms of host defense, including leukocyte recruitment, edema, bacterial clearance and lung injury/resolution. Although these processes are important in all inflammatory lung diseases, her work particularly addresses pneumonia and the acute respiratory distress syndrome using in vivo, translational, cell biological, immunological, and molecular approaches. These studies investigate pathogens that cause community-acquired and nosocomial pneumonias occurring in immunocompromised patients, including those with cancer. Her ultimate goal is to use this knowledge to develop therapies that enhance the inflammatory response when it is beneficial to the host and dampen this response when it is harmful.
研究兴趣
论文共 54 篇作者统计合作学者相似作者
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Morgan J. McCullough, Miriya K. Tune, Johnny Castillo Cabrera,Jose Torres-Castillo,Minghong He,Yongqiang Feng,Claire M. Doerschuk,Hong Dang, Adriana S. Beltran,Robert S. Hagan,Jason R. Mock
IMMUNOLOGY AND CELL BIOLOGYno. 3 (2024): 211-224
Journal of leukocyte biologyno. 1 (2024): 1-3
JOURNAL OF LEUKOCYTE BIOLOGYno. 1 (2024): 1-3
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Chestno. 3 (2023): 502-514
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American Journal of Respiratory Cell and Molecular Biology (2022)
American Journal of Respiratory and Critical Care Medicine (2022)
American Journal of Respiratory Cell and Molecular Biology (2022)
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