基本信息
浏览量:1
职业迁徙
个人简介
As an investigator in John Perfect's laboratory, I have continued to study the molecular pathogenesis of Cryptococcus neoformans. We are interested in identifying virulence genes expressed by the fungus during infection using our rabbit model of cryptococcal meningitis and during in vitro exposure to the pathological temperature of 37 degrees C. By PCR differential display, we are identifying genes associated with pathogenesis of the organism and assessing their effects at the molecular level using a 2-hybrid system. In addition, we are disrupting targeted virulence genes using biolistic transformation and assessing their role in the virulence of C neoformans in rabbit and murine models of cryptococcal disease.
研究兴趣
论文共 12 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Thanh Tuan Lam,Dena Toffaletti,Jennifer Tenor, Charles Giamberardino, D. Gregory, Sempowski, Yohannes Asfaw, Trieu Hai Phan, Anh Van Duong, Trinh Mai Nguyen,Lan Phu,Huong Nguyen,
semanticscholar(2017)
引用0浏览0引用
0
0
crossref(2017)
Thanh Tuan Lam,Dena Toffaletti,Jennifer Tenor,Charles Giamberardino, D. Gregory, Sempowski, Yohannes Asfaw,Trieu Hai Phan, Anh Van Duong,Trinh Mai Nguyen,Lan Phu,Huong Nguyen,
semanticscholar(2017)
引用0浏览0引用
0
0
Chiara Luberto, Beatriz Martinez-Mariño, Daniel Taraskiewicz, Benjamin Bolaños, Pasquale Chitano,Dena L Toffaletti,Gary M Cox,John R Perfect,Yusuf A Hannun, Edward Balish,Maurizio Del Poeta
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn