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Our laboratory is specialized on mass spectrometric approaches to study the involvement of lipid signaling molecules in the development of different pulmonary diseases. Our main current focus is at sphingolipid signaling molecules as the inducers and modulators of COPD and pulmonary fibrosis. In particular, we have established an important link between sphingolipid de novo biosynthesis and the development of emphysema. We also investigate how natural, synthetic, and endogenous ligands for cannabinoid receptors affect fibrotic processes in the lung. Another focus area for our group is the involvement of polyunsaturated molecular species of lysophosphatidic acids in the allergic responses in the lung. We try to understand metabolic pathways involved and sources of lysophosphatidic acid production in the lung and to link lysophosphatidic acid generation to the severity and subtypes of asthma.
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论文共 258 篇作者统计合作学者相似作者
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Melinda Braskett,Elena Goleva,Irina Bronova, Gautam Nagendra,Ramon Durazo-Arvizu, Nick Shillingford, Harry Cynamon, Mika Warren,Vrinda Bhardwaj,Peck Ong, Donald Leung,Evgeny Berdyshev,
Journal of Allergy and Clinical Immunologyno. 2 (2024): AB248
J. M. Poczobutt, C. F. Cornell, N. W. Egersdorf,A. Borowiec,K. Kopf, B. Babbs, R. Tanner, B. Dubois, T. Saltzman,J. Matsuda,E. Berdyshev, I. Bronova,
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AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2023)
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Irina Petrache,Elisabet Pujadas, Aditya Ganju,Karina A Serban,Alexander Borowiec, Beatrice Babbs,Irina A Bronova,Nicholas Egersdorf,Patrick S Hume,Khushboo Goel,William J Janssen,Evgeny V Berdyshev,
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Journal of Allergy and Clinical Immunologyno. 5 (2023): 1307-1316
E. Goleva,E. Berdyshev,R. Bissonnette,S. Kreimer, T. Lyubchenko,S. Bafna, I. Agueusop, N. Levit, A. Zhang,D. Leung
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