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Research interests
The laboratory primarily focuses on synapses, which are the point of communication between brain cells. We are interested in normal synaptic function and synapse dysfuntion. Synaptic dysfunction is emerging as a key player in many brain disorders. We use patch-clamp electrophysiology and optogenetics in brain slices, immunohistochemistry and biochemical assays to study synaptic properties and synaptic plasticity that may participate in physiological or pathophysiological processes. Of particular interest are the synaptic changes or plasticity that may be responsible for chronic pain states, addiction and anxiety disorders. We also use behavioural assays to try to understand the role of these synaptic changes in the whole animal.
The laboratory primarily focuses on synapses, which are the point of communication between brain cells. We are interested in normal synaptic function and synapse dysfuntion. Synaptic dysfunction is emerging as a key player in many brain disorders. We use patch-clamp electrophysiology and optogenetics in brain slices, immunohistochemistry and biochemical assays to study synaptic properties and synaptic plasticity that may participate in physiological or pathophysiological processes. Of particular interest are the synaptic changes or plasticity that may be responsible for chronic pain states, addiction and anxiety disorders. We also use behavioural assays to try to understand the role of these synaptic changes in the whole animal.
研究兴趣
论文共 28 篇作者统计合作学者相似作者
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biorxiv(2021)
Samantha M Solon-Biet,Victoria C Cogger,Tamara Pulpitel,Devin Wahl, Ximonie Clark,Elena Bagley,Gabrielle C Gregoriou,Alistair M Senior,Qiao-Ping Wang,Amanda E Brandon,Ruth Perks,John O’Sullivan,
semanticscholar(2019)
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