基本信息
views: 52
Career Trajectory
Bio
I obtained my PhD in microbiology and molecular biology at Paris XI University in 2000. My PhD work, carried under the supervision of P. Renault, focused on the regulation of the proteolytic system of Lactococcus lactisby CodY, a pleiotropic transcriptional factor. In March 2000, I joined the group of Tarek Msadek at Pasteur Institute (Paris) to study the mechanisms of transcriptional regulation by two-component systems in Bacillus subtilis. In September 2001, I was appointed as permanent INRA research scientist in the Génétique Microbienne lab headed by S.D. Ehrlich (INRA, Jouy-en-Josas) where I joined the BAC team to work on the molecular mechanisms of adaptation, including genetic and genomic modifications, of Streptococci to environmental changes. In 2010, I joined the Micalis institute (INRA, Jouy-en-Josas) to work on commensal bacteria of the human gut microbiota in the frame of the MetaHit EU project. In 2015, I moved to UMR1253 STLO (INRA-Agrocampus Ouest, Rennes) to develop works on intercellular communication and bacterial extracellular vesicles and to lead the Microbio team. In January 2017, I was promoted INRA Senior Researcher (Directeur de Recherches INRA).
From my PhD to now, the main focus of my research has always been the study of interactions and adaptation to environment of Gram-positive bacteria in order to gain a better understanding of how bacterial cell function. I have developed an expertise in microbiology, molecular genetics, genomic and post-genomic through works on the mechanisms of gene expression control, analysis of bacterial functions, genome evolution and bacterial-host interactions. My background reflects my curiosity and my interest for original, collaborative and multidisciplinary projects related to food and human health. Initially centering on lactic acid bacteria to improve the quality of fermented foods, my research activity evolved towards the study of commensal bacteria to unravel the mechanisms of their beneficial effects on human health and wellness. I participated to the pioneer works on the human intestinal microbiota at the UMR Micalis (INRA, Jouy-en-Josas). To further explore the relations between fermented foods, microbiota and host health, I joined the UMR STLO in 2015, in which I currently lead the MicroBio team. Our team shares a common ambition: to better understand the functioning of bacterial communities in relation with food and mammals in order to provide knowledge for their management and functionalization. For my part, I initiated studies on intra- and inter-species interactions and mechanisms of dialogue. In particular, my main interest now resides on extracellular vesicles (i.e. exosomes, EVs), nanoparticles produced by bacteria, and their role as mediators in communication with other bacteria, the microbiota and the host.
Research Interests
Papers共 179 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Probiotics and Antimicrobial Proteinspp.1-37, (2024)
Applied and environmental microbiology (2024)
Juliana Guimaraes Laguna,Andria dos Santos Freitas,Fernanda Alvarenga Lima Barroso,Luis Claudio Lima De Jesus, Octavio Augusto Greco Gomes De Vasconcelos,Ludmila Silva Quaresma,Monique Ferrary Americo,Gabriela Munis Campos,Rafael de Assis Gloria,Joyce da Cruz Ferraz Dutra,Tales Fernando Da Silva,Katia Duarte Vital,Simone O. Fernandes,Ramon O. Souza,Flaviano dos Santos Martins,Enio Ferreira,Tulio Marcos Santos,Alexander Birbrair, Marcos Felipe Andrade De Oliveira,Ana Maria Caetano Faria,Rodrigo Dias de Oliveira Carvalho,Franco Maria Venanzi,Yves Le Loir,Gwenael Jan,Eric Guedon,Vasco Ariston de Carvalho Azevedo
Marine Mantel,Tony Durand,Anne Bessard, Segolene Pernet, Julie Beaudeau, Juliana Guimaraes-Laguna,Marie-Bernadette Maillard,Eric Guedon,Michel Neunlist,Yves Le Loir,Gwenael Jan, Malvyne Rolli-Derkinderen
American journal of physiology Gastrointestinal and liver physiology/American journal of physiology Gastrointestinal and liver physiologyno. 2 (2024): G163-G175
openalex(2024)
Cited0Views0Bibtex
0
0
Frontiers in immunology (2023)
Journal of extracellular biologyno. 2 (2023): e75-e75
Research Square (Research Square) (2023)
Load More
Author Statistics
#Papers: 183
#Citation: 9461
H-Index: 40
G-Index: 96
Sociability: 6
Diversity: 3
Activity: 48
Co-Author
Co-Institution
D-Core
- 合作者
- 学生
- 导师
Data Disclaimer
The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn