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个人简介
My work as a physician-scientist involves both the care of cancer patients and biomedical research directed toward a greater understanding of the mechanisms involved in malignant transformation. My laboratory focuses on understanding the cooperative interactions that conspire to transform human cells. To address this question, we have developed new experimental models of human cancer of defined genetic composition, created methods to perform systematic interrogation of gene function in mammalian cells and tissues and help optimize new approaches to integrate genome scale data. Using these approaches, we have identified and credential new oncogenes and tumor suppressor genes and have performed preclinical studies that will form the foundation necessary for translational studies in patients.
研究兴趣
论文共 327 篇作者统计合作学者相似作者
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Nature Medicinepp.1-1, (2024)
Cancer researchno. 6 (2024): 935-935
CANCER RESEARCHno. 6 (2024): 935-935
Andrew L. Hong,Jennifer L. Guerriero,Mihir B. Doshi, Bryan D. Kynnap,Won Jun Kim,Anna C. Schinzel, Rebecca Modiste, Amy J. Schlauch,Rosalyn M. Adam,David J. Kwiatkowski,Rameen Beroukhim,Anthony Letaï,
openalex(2023)
Judit Jané-Valbuena,Hans R. Widlund,Sven Perner,Laura A. Johnson, Aurora C. Dibner,William M. Lin, Alissa C. Baker,Rosalynn M. Nazarian, Krishna G. Vijayendran,William R. Sellers,William C. Hahn,Lyn M. Duncan,
crossref(2023)
Kimberly R. Hagel,Rand Arafeh,Sydney Gang,Taylor E. Arnoff,Rebecca C. Larson,John G. Doench,Nathan D. Mathewson,Kai W. Wucherpfennig, Marcela V. Maus,William C. Hahn
crossref(2023)
Veronica Rendo,Michael Schubert,Nicholas Khuu, Maria F Suarez Peredo Rodriguez,Kaimeng Huang,Michelle Swift, Yizhou He,Johanna Zerbib,Ross Smith,Jonne Raaijmakers,Pratiti Bandopadhayay,Lillian M. Guenther,
biorxiv(2023)
crossref(2023)
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