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个人简介
Isabel B. Leonor received her PhD in Materials Science and Technology - Biomaterials from the University of Minho, under the supervision of Prof. T. Kokubo (University of Kyoto, Japan) and Prof. R. Reis. Her PhD work was focused on developing new approaches for the surface functionalization of materials in bone repair.
During her Master in Polymer Engineering, she had the opportunity to work in the Advanced Biomaterials Group with Prof. Atsuo Ito (Inst. for Human Science and Biomedical Eng., AIST, Japan) studying the formation of calcium phosphate layer on osteoconductive materials by using in situ atomic force microscopy. During her post-doc she investigated the influence of silanol groups on the osteogenic differentiation of mesenchymal stem cells. In September 2011 she was appointed as research fellow in the 3B’s Research Group, where she has been working since its genesis. Her research interests are focused on developing bioactive materials, addressing the importance of highly organized functionalized surfaces towards the controlled nucleation of apatite and the osteogenic differentiation of stem cells; and in using recombinant DNA technology to generate spider silk chimeric proteins with different functionalities, cell adhesion, apatite nucleation and antibacterial motifs, towards their application in tissue engineering and infection control of implants. She is also interested in studying the effect of nanotopographical features on bacteria adhesion to design antibacterial surfaces. Currently, she is focused in developing tools and methods for the morphological and structural analysis of materials using a wide range of advanced microscopy and spectroscopy techniques.
研究兴趣
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JOURNAL OF COMPOSITES SCIENCEno. 3 (2024): 85
Albina Franco,Marta Casanova,Albino Martins,Nuno Neves,Isabel Leonor, Rui Reis, Daniela Cruz-Moreira
TISSUE ENGINEERING PART Ano. 11-12 (2023): 1410-1411
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Elisabeth Amann,Amisel Amirall,Albina R Franco,Patrina S P Poh, Francisco J Sola Dueñas, Gastón Fuentes Estévez,Isabel B Leonor, Rui L Reis,Martijn van Griensven,Elizabeth R Balmayor
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