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Jörg was a leader in the application of fluorescence-based methods to the study of the nucleus as well as other aspects of cell biology, and was also a pioneer in the application of polymer physics to the study of DNA and chromosomes. To those who had the privilege of knowing him, he was a valued, amiable, often boisterous friend and colleague, a “born” biophysicist and, at the same time, a critical, astute observer of the human condition.
A major contribution of Jörg and his colleagues was the measurement of the fluid viscosity of the inter-chromatin space in the nucleus by fluorescence correlation spectroscopy of GFP. This value could not have come at a more propitious moment because a boomlet of FRAP studies of nuclear proteins as well as new measurements of the apparently diffusive movements of RNAs in the nucleus were just then appearing. Technically, Jörg was always at the cutting edge, as in single molecule spectroscopy and various additional advanced microscopy techniques with the acronyms TIRF, AFM and SPIM. However, the theoretical underpinning of his research was paramount, as exemplified in the modeling of the dynamics of chromosomes and their substructures.
To those of us who had the great privilege and pleasure of knowing him, Jörg was a constant beacon of energy and passion, a person of great intellectual breadth accompanied by a joy of life that was the most cherished “infection” any of us had ever had, with us wishing for no antibiotic. He enlivened conferences by his dynamic oratory from the rostrum but could be even more spellbinding in the delightfully penetrative questions he posed to other speakers, always doing so with great intensity.
A major contribution of Jörg and his colleagues was the measurement of the fluid viscosity of the inter-chromatin space in the nucleus by fluorescence correlation spectroscopy of GFP. This value could not have come at a more propitious moment because a boomlet of FRAP studies of nuclear proteins as well as new measurements of the apparently diffusive movements of RNAs in the nucleus were just then appearing. Technically, Jörg was always at the cutting edge, as in single molecule spectroscopy and various additional advanced microscopy techniques with the acronyms TIRF, AFM and SPIM. However, the theoretical underpinning of his research was paramount, as exemplified in the modeling of the dynamics of chromosomes and their substructures.
To those of us who had the great privilege and pleasure of knowing him, Jörg was a constant beacon of energy and passion, a person of great intellectual breadth accompanied by a joy of life that was the most cherished “infection” any of us had ever had, with us wishing for no antibiotic. He enlivened conferences by his dynamic oratory from the rostrum but could be even more spellbinding in the delightfully penetrative questions he posed to other speakers, always doing so with great intensity.
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Biophysical Journalno. 10 (2018): 2386-2396
Norbert Mücke, Lara Kämmerer,Stefan Winheim,Robert Kirmse,Jan Krieger, Maria Mildenberger,Jochen Baßler,Ed Hurt,Wolfgang H Goldmann,Ueli Aebi,Katalin Toth,Jörg Langowski,
Biophysical journalno. 10 (2018): 2465-2472
Paul Victor Sauer, Jennifer Timm,Danni Liu,David Sitbon, Elisabetta Boeri-Erba,Christophe Velours,Norbert Mücke,Jörg Langowski,Françoise Ochsenbein,Geneviève Almouzni, Daniel Panne
crossref(2017)
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