Jens Juergen Quant - Boehringer Ingelheim Austria GmbH

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论文共 21 篇作者统计合作学者相似作者

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Discovery and Characterization of Brigimadlin, a Novel and Highly Potent MDM2-p53 Antagonist Suitable for Intermittent Dose Schedules

Andreas Gollner,Dorothea Rudolph,Ulrike Weyer-Czernilofsky, Rosa Baumgartinger, Peter Jung,Harald Weinstabl, Jürgen Ramharter,Rolf Grempler,Jens Quant,Jörg Rinnenthal, Alejandro Pérez Pitarch, Bojana Golubovic,Daniel Gerlach,Gerd Bader, Kristiane Wetzel, Sebastian Otto, Christian Mandl,Guido Boehmelt,Darryl B McConnell, Norbert Kraut,Patrizia Sini

Molecular cancer therapeutics (2024)

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Targeting Cancer with Small-Molecule Pan-Kras Degraders

Johannes Popow,William Farnaby, Andreas Gollner,Christiane Kofink,Gerhard Fischer, Melanie Wurm,David Zollman,Andre Wijaya,Nikolai Mischerikow, Carina Hasenoehrl,Polina Prokofeva,Heribert Arnhof, Silvia Arce-Solano, Sammy Bell, Georg Boeck,Emelyne Diers, Aileen B Frost, Jake Goodwin-Tindall,Jale Karolyi-Oezguer, Shakil Khan, Theresa Klawatsch,Manfred Koegl, Roland Kousek, Barbara Kratochvil, Katrin Kropatsch, Arnel A Lauber,Ross McLennan,Sabine Olt, Daniel Peter, Oliver Petermann, Vanessa Roessler, Peggy Stolt-Bergner, Patrick Strack, Eva Strauss,Nicole Trainor,Vesna Vetma,Claire Whitworth, Siying Zhong,Jens Quant,Harald Weinstabl,Bernhard Kuster,Peter Ettmayer,Alessio Ciulli

Science (New York, NY)no. 6715 (2024): 1338-1347

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Supplementary Methods, Figure 1, Table 1 from BIBF 1120: Triple Angiokinase Inhibitor with Sustained Receptor Blockade and Good Antitumor Efficacy

Frank Hilberg,Gerald J. Roth,Martin Krssak,Susanna Kautschitsch,Wolfgang Sommergruber,Ulrike Tontsch-Grunt,Pilar Garin-Chesa,Gerd Bader,Andreas Zoephel,Jens Quant,Armin Heckel,Wolfgang J. Rettig

crossref（2023）

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Supplementary Figure S2: Western Blot Analysis of MAPK Pathway Inhibition by BI 847325 in BRAF-mutant Cell Lines. from Pharmacological Profile of BI 847325, an Orally Bioavailable, ATP-Competitive Inhibitor of MEK and Aurora Kinases

Patrizia Sini,Ulrich Gürtler,Stephan K. Zahn, Christoph Baumann,Dorothea Rudolph, Rosa Baumgartinger, Eva Strauss,Christian Haslinger, Ulrike Tontsch-Grunt,Irene C. Waizenegger,Flavio Solca,Gerd Bader, Andreas Zoephel,Matthias Treu,Ulrich Reiser,Pilar Garin-Chesa,Guido Boehmelt, Norbert Kraut,Jens Quant,Günther R. Adolf

crossref（2023）

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Targeting cancer with small molecule pan-KRAS degraders

Johannes Popow,William Farnaby,Andreas Gollner, Christiane Kofink,Gerhard Fischer,Melanie Wurm,David Zollman,Andre Wijaya,Nikolai Mischerikow, Carina Hasenoehrl,Polina Prokofeva,Heribert Arnhof, Silvia Arce-Solano, Sammy Bell, Georg Boeck,Emelyne Diers, Aileen B. Frost, Jake Goodwin-Tindall,Jale Karolyi-Oezguer, Shakil Khan, Theresa Klawatsch,Manfred Koegl,Roland Kousek, Barbara Kratochvil, Katrin Kropatsch, Arnel A. Lauber,Ross McLennan,Sabine Olt, Daniel Peter,Oliver Petermann, Vanessa Roessler,Peggy Stolt-Bergner,Patrick Strack,Eva Strauss,Nicole Trainor,Vesna Vetma,Claire Whitworth, Siying Zhong,Jens Quant,Harald Weinstabl,Bernhard Kuster,Peter Ettmayer,Alessio Ciulli

biorxiv（2023）

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Intracellular Trapping of the Selective Phosphoglycerate Dehydrogenase (PHGDH) Inhibitor BI-4924 Disrupts Serine Biosynthesis

Harald Weinstabl,Matthias Treu,Joerg Rinnenthal,Stephan K. Zahn,Peter Ettmayer,Gerd Bader,Georg Dahmann,Dirk Kessler,Klaus Rumpel,Nikolai Mischerikow,Fabio Savarese, Thomas Gerstberger,Moriz Mayer,Andreas Zoephel,Renate Schnitzer,Wolfgang Sommergruber,Paola Martinelli,Heribert Arnhof,Biljana Peric-Simov,Karin S. Hofbauer,Geraldine Garavel, Yvonne Scherbantin,Sophie Mitzner,Thomas N. Fett,Guido Scholz,Jens Bruchhaus, Michelle Burkard,Roland Kousek,Tuncay Ciftci,Bernadette Sharps,Andreas Schrenk, Christoph Harrer,Daniela Haerinsg,Bernhard Wolkerstorfer,Xuechun Zhang,Xiaobing Lv,Alicia Du, Dongyang Li,Yali Li,Jens Quant,Mark Pearson,Darryl B. McConnell

Journal of medicinal chemistry（2019）

引用44浏览0WOS引用

Efficacy of the Highly Selective Focal Adhesion Kinase Inhibitor BI 853520 in Adenocarcinoma Xenograft Models is Linked to a Mesenchymal Tumor Phenotype

Ulrich A. Hirt,Irene C. Waizenegger,Norbert Schweifer,Christian Haslinger,Daniel Gerlach,Jürgen Braunger,Ulrike Weyer-Czernilofsky,Heinz Stadtmüller,Ioannis Sapountzis,Gerd Bader,Andreas Zoephel, Bojan Bister,Anke Baum,Jens Quant,Norbert Kraut,Pilar Garin-Chesa,Günther R. Adolf

Oncogenesis（2018）

引用40浏览0WOSNATURE引用

A novel, potent MDM2 inhibitor that is suitable for high-dose intermittent schedules

Dorothea Rudolph,Andreas Gollner,Sophia Blake,Joerg Rinnenthal,Andreas Wernitznig,Ulrike Weyer-Czernilofsky,Christian Haslinger,Pilar Garin-Chesa,Jens Quant,Darryl B. McConnell,Juergen Moll,Kraut Norbert

CANCER RESEARCH（2018）

引用5浏览0引用

Abstract 4866: BI 907828: A Novel, Potent MDM2 Inhibitor That Induces Antitumor Immunologic Memory and Acts Synergistically with an Anti-Pd-1 Antibody in Syngeneic Mouse Models of Cancer

Dorothea Rudolph,Markus Reschke,Sophia Blake,Joerg Rinnenthal,Andreas Wernitznig,Ulrike Weyer-Czernilofsky,Andreas Gollner,Christian Haslinger,Pilar Garin-Chesa,Jens Quant,Darryl B. McConnell,Kraut Norbert,Juergen Moll

Cancer Research（2018）

引用11浏览0引用

Abstract 4865: BI 907828: A Highly Potent MDM2 Inhibitor with Low Human Dose Estimation, Designed for High-Dose Intermittent Schedules in the Clinic

Joerg Rinnenthal,Dorothea Rudolph,Sophia Blake,Andreas Gollner,Andreas Wernitznig,Ulrike Weyer-Czernilofsky,Christian Haslinger,Pilar Garin-Chesa,Juergen Moll,Norbert Kraut,Darryl McConnell,Jens Quant

Cancer research（2018）

引用10浏览0引用

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