I am interested in enabling practitioners of biomolecular simulations in three primary ways: By creating methods that enable the semi-automatic creation of reduced models for understanding kinetics and thermodynamics of biomolecules. An example is our recently developed Normal Mode splitting of molecular dynamics, which allows for 10-1000 speedups over conventional simulation. By creating methods that enable the prediction and validation of domain-domain and protein-protein interactions in different organisms. We are combining biological and structural systems biology. Finally, I am interested in making these techniques available through well-built software.