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He is a world leader in prostate cancer research, having changed the treatment of prostate cancer multiple times through trials of the ICR-discovered drug abiraterone, cabazitaxel, enzalutamide and olaparib. He also led on the identification of germline and somatic DNA repair defects in lethal prostate cancer, and co-led studies mapping the genomics of these diseases. His work has changed international guidelines on germline testing in men with advanced prostate cancer and the first molecular stratification for this commonest of male cancers. He has also recently led studies of pembrolizumab, talazoparib, ipatasertib and lutetium-PSMA for men suffering from advanced prostate cancer.
研究兴趣
论文共 39 篇作者统计合作学者相似作者
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CANCER RESEARCHno. 8 (2023): CT093-CT093
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Juliet Richards, Ai Chiin Lim,Colin W. Hay,Angela E. Taylor,Anna Wingate,Karolina Nowakowska,Carmel Pezaro,Suzanne Carreira,Jane Goodall,Wiebke Arlt,Iain J. McEwan,Johann S. de Bono,
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Christina Guo,Adam Sharp,Bora Gurel,Mateus Crespo,Ines Figueiredo,Suneil Jain, Ursula Vogl,Jan Rekowski, Mahtab Rouhifard,Lewis Gallagher,Wei Yuan,Suzanne Carreira,
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Anthony W. Tolcher,Timothy A. Yap, Ruth Plummer, Thomas Grombacher, Danyi Wang, Corinna Schaffroth, Christine Hicking, Zoltan Szucs, Giuseppe Locatelli,Johann S. de Bono
CANCER RESEARCHno. 8 (2023)
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