基本信息
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职业迁徙
个人简介
Research Interest Summary
Large scale discovery of protein-protein interactions and their application to understanding of disease mechanisms
Research Categories
Computational Biology
Genomics
Proteomics
Research Interests
Primary focus of our group is on prediction, analysis and dissemination of novel protein-protein interactions of human genes. Our work on predicting mental health and inflammation (MHAIN) interactome (namely protein-protein interactions where at least one of the two proteins is involved in mental health or inflammation, is funded by the NIMH BRAINS award. On the algorithm development side, we employ machine learning, including active learning and transfer learning approaches to predict interactions. We also develop methods to analyze interaction network to draw biologically relevant inferences and disseminate them effectively to biologists. We are currently studying the role of cilia and inflammation in different diseases such as schizophrenia and congenital heart disease, through collaborations with faculty from Developmental Biology and Psychiatry.
Large scale discovery of protein-protein interactions and their application to understanding of disease mechanisms
Research Categories
Computational Biology
Genomics
Proteomics
Research Interests
Primary focus of our group is on prediction, analysis and dissemination of novel protein-protein interactions of human genes. Our work on predicting mental health and inflammation (MHAIN) interactome (namely protein-protein interactions where at least one of the two proteins is involved in mental health or inflammation, is funded by the NIMH BRAINS award. On the algorithm development side, we employ machine learning, including active learning and transfer learning approaches to predict interactions. We also develop methods to analyze interaction network to draw biologically relevant inferences and disseminate them effectively to biologists. We are currently studying the role of cilia and inflammation in different diseases such as schizophrenia and congenital heart disease, through collaborations with faculty from Developmental Biology and Psychiatry.
研究兴趣
论文共 111 篇作者统计合作学者相似作者
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George C Gabriel,Hisato Yagi,Tuantuan Tan,Abha S Bais, Benjamin J Glennon,Margaret C Stapleton, Lihua Huang,William T Reynolds, Marla G Shaffer,Madhavi Ganapathiraju,Dennis Simon,Ashok Panigrahy,
bioRxiv : the preprint server for biology (2024)
Annual review of genomics and human genetics (2024)
Schizophreniano. 1 (2024): 1-1
Frontiers in Systems Biology (2023)
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European Journal of Neuroscienceno. 3 (2022): 675-693
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