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Dr. McCarthy conducted some of the first studies on how steroid hormones can imprint epigenetically on the developing brain to organize differences between males and females in adult physiology and behavior. More recently, her laboratory generated a paradigm shift in understanding of sexual differentiation of sexual behavior with the discovery that the feminization program of development requires suppression of the masculinization program via DNA methylation, and that steroid hormones emancipate the male gene expression profile by reducing activity of DNA methylating enzymes.
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Natureno. 8010 (2024): 37-40
Nature (2024)
Margaret M. McCarthy,Jason Fletcher,Fay Wright, Ines Del Giudice,Agnes Wong,Bradley E. Aouizerat,Victoria Vaughan Dickson, Gail D'Eramo Melkus
BIOLOGICAL RESEARCH FOR NURSINGpp.10998004241238237-10998004241238237, (2024)
Natureno. 8010 (2024): 37-40
Nursing researchno. 3 (2023): 185-192
Lise Eliot,Annaliese K. Beery,Emily G. Jacobs, Hannah F. LeBlanc,Donna L. Maney,Margaret M. McCarthy
JOURNAL OF NEUROSCIENCEno. 37 (2023): 6344-6356
ANNUAL REVIEW OF NEUROSCIENCEno. 1 (2023): 321-339
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