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Maria Iandolo New is a professor of Pediatrics, Genomics and Genetics at Icahn School of Medicine at Mount Sinai in New York City.[1] She is an expert in congenital adrenal hyperplasia (CAH), a genetic disorder affecting the adrenal gland.
Dr. Maria New earned her undergraduate degree from Cornell University in Ithaca, New York, in 1950, and her M. D. from the Perelman School of Medicine at the University of Pennsylvania in Philadelphia, in 1954. She completed an internship in medicine at Bellevue Hospital in New York, followed by a residency in pediatrics at the New York Hospital. From 1957 to 1958 she studied renal functioning under a fellowship from the National Institutes of Health (NIH). She was a research pediatrician to the Diabetic Study Group of the Comprehensive Care Teaching Program at the New York Hospital-Cornell Medical Center from 1958 to 1961, and had a second NIH fellowship under Ralph E. Peterson from 1961 to 1964, to study specific steroid hormone production during infancy, childhood and adolescence.
In 1964, Dr. New was appointed Chief of Pediatric Endocrinology at Cornell University Medical College, a position she held for 40 years. In 1978, she was named Harold and Percy Uris Professor of Pediatric Endocrinology and Metabolism. In 1980, Dr. New was appointed Chairman of the Department of Pediatrics at Cornell University Medical College and Pediatrician-in-Chief of the Department of Pediatrics at New York-Presbyterian Hospital. She was one of the few women in the country to serve as Chair of a major division of a medical college, and hertenure lasted for 22 years. While Chairman, Dr. New founded and directed the 8-bed Children's Clinical Research Center, a clinical research center in pediatrics with groundbreaking research in pediatric endocrinology, hematology, and immunology, during the emergence of AIDS. In 2004, Dr. New was recruited to the Mount Sinai School of Medicine as Professor of Pediatrics and Human Genetics and Director of the Adrenal Steroid Disorders Program.[3] She is also currently Adjunct Professor of Genetics at Columbia College of Physicians and Surgeons, and Associate Dean for Research at the Herbert Wertheim College of Medicine at Florida International University.
Dr. New is recognized as one of the world's leading pediatric endocrinologists.[4] Her career exemplifies the link between clinical and basic science. She has continued her scientific research, pioneering the use of molecular genetic diagnosis, prenatal diagnosis and treatment. Although steroid physiology was well understood when Dr. New began her scientific career, little of the knowledge had been applied to the understanding of steroid disorders in children. Dr. New's seminal research on the mechanism and genetics of steroid disorders has established standards for pre- and post-natal care for patients with congenital adrenal hyperplasia and apparent mineralocorticoid excess.
During a 43-year period, Dr. New held the longest continuously funded National Institutes of Health grant, "Androgen Metabolism in Childhood", which supported research characterizing the diverse clinical spectra of patients with rare steroidogenic enzyme defects, such as congenital adrenal hyperplasia, and the metabolic consequences of those defects.[5]
Her current primary research emphasis is on genetic steroid disorders. Dr. New continues to study three monogenic disorders: 21-hydroxylase deficiency, 11β-hydroxylase deficiency, and apparent mineralocorticoid excess, emphasizing genotype/phenotype correlation and prenatal diagnosis and treatment. She has published more than 640 academic articles in a wide range of prestigious journals and published a genetics book entitled Genetic Steroid Disorders in 2014. This book contains chapters by the leaders in the world of the field of genetic adrenal disorders. She has also received numerous awards and recognition for her work treating mothers and children affected with the disorder.
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Elsevier eBookspp.111-121, (2023)
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Sakshi Gera,Damini Sant,Shozeb Haider,Funda Korkmaz,Tan-Chun Kuo,Mehr Mathew,Helena Perez-Pena, Honglin Xie,Hao Chen,Rogerio Batista, Kejun Ma,Zhen Cheng,
MATERNAL-FETAL AND NEONATAL ENDOCRINOLOGY: PHYSIOLOGY, PATHOPHYSIOLOGY, AND CLINICAL MANAGEMENT (2020)
Encyclopedia of Bone Biologypp.723-729, (2020)
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