基本信息
浏览量:2
职业迁徙
个人简介
Mechanisms and therapeutics for autism and pain
Recent whole exome sequencing studies identified hundreds of genes linked to autism, many of which are transcriptional regulators. My lab is studying a number of these transcriptional regulators using genome-wide approaches to determine how they contribute to autism. This work includes cellular and behavioral studies with neuronal cultures and autism mouse models. We are also using high-throughput sequencing approaches to identify chemical risk factors for autism and other brain disorders, including neurodegeneration.
Our pain research is focused on studying a number of lipid kinases, some of which may represent new therapeutic targets for chronic pain. We are also using circuit-based approaches to dissect pain pathways in the periphery and in the brain. A key goal is to better understand the molecules and circuits that transduce pain so that new therapeutics can be developed.
研究兴趣
论文共 34 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Eric S. McCoy,Sang Kyoon Park,Rahul P. Patel, Dan F. Ryan,Zachary J. Mullen, Jacob J. Nesbitt, Josh E. Lopez,Bonnie Taylor-Blake, James L. Krantz,Wenxin Hu, Rosanna L. Garris,Lucas V. Lima,
biorxiv(2022)
Alexander H Tuttle, Mark J Molinaro, Jasmine F Jethwa,Susana G Sotocinal,Juan C Prieto,Martin A Styner,Jeffrey S Mogil,Mark J Zylka
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn