基本信息
浏览量:6
职业迁徙
个人简介
Dr Schneider is an internationally known leader in skeletal muscle excitation-contraction coupling, the series of steps whereby electrical depolarization of the normally inside negative muscle membrane potential initiates release of calcium ions (Ca2+) from their intracellular storage location, the muscle sarcoplasmic reticulum (SR), allowing Ca2+ ions bind to regulatory sites on muscle contractile filaments, which serves as a switch to permit contractile filament interaction, producing force development and muscle shortening. In pioneering work in collaboration with his post doc mentor Dr W.K. Chandler (Yale University), Dr Schneider made the first measurements of tiny electrical currents (charge displacement currents or channel “gating” currents) due to the redistribution of charged voltage sensor proteins within the muscle membrane. Such gating currents were previously predicted in the classic studies of Hodgkin and Huxley on voltage dependent channel activation underlying the action potential in nerve axons, and were first detected in any excitable cell membrane by Schneider and Chandler in skeletal muscle, where they control Ca2+ release from Ca2+ release channels in the spatially immediately adjacent SR membrane. Analogous gating currents were subsequently identified by other groups for gating voltage dependent Na+, K+ and Ca2+ channels in other excitable cells.
研究兴趣
论文共 367 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Naita M. Wirsik, Pia C. Appel, Alexander Braun,Moritz J. Strowitzki,Nikolai Schleussner,Henrik Nienhüser,Martin Schneider, Thomas Schmidt
Journal of Surgical Research (2024): 176-184
Alina S. Ritter, Noemi Dumm, Julian M. Deisenhofer,Clemens Franz,Mohammed Al-Saeedi,Markus W. Buechler,Martin Schneider
DISEASES OF THE COLON & RECTUMno. 1 (2024): 138-150
Julia Schöpf,Sebastian Uhrig,Christoph E Heilig,Kwang-Seok Lee,Tatjana Walther, Alexander Carazzato,Anna Maria Dobberkau,Dieter Weichenhan,Christoph Plass,Mark Hartmann,Gaurav D Diwan,Zunamys I Carrero,
Martin Loos, Claudia E. Mack, An Ting L. Xu,Matthias Hassenpflug,Ulf Hinz,Arianeb Mehrabi,Christoph Berchtold,Martin Schneider,Mohammed Al-Saeedi,Susanne Roth,Thilo Hackert,Markus W. Buechler
biorxiv(2024)
Georgios Makridis,Tim Reese,Zoltan S. Zadori,Anna I. Suling,Maria Stark, Katja Horling,Roland Bruening,Martin A. Schneider, Michael Beumer,Karl J. Oldhafer
HPBno. 1 (2024): 91-101
Laura B Oswald, Amanda Bloomer, Xiaoyin Li, Esther Jean-Baptiste,Gillian Trujillo, Seth Felder,Brent J Small,Jennifer Ose,Sheetal Hardikar, Ildiko Strehli,Lyen C Huang,Kathi Mooney,
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancerno. 5 (2024): 298-298
Tolga Lokumcu, Murat Iskar,Martin Schneider, Dominic Helm,Glynis Klinke,Lisa Schlicker,Frederic Bethke, Gabriele Mu''ller, Karsten Richter,Gernot Poschet,Emma Phillips,Violaine Goidts
ACS NANOno. 3 (2024): 2500-2519
Naita Maren Wirsik, Mingyi Chen, Liping He, Uraz Yasar, Justus Gaukel,Alexander Quaas,Henrik Nienhueser, Ella Leugner, Shuai Yuan,Nikolai Schleussner,Jin-On Jung, Jadie Sue Pluecker,
Changwen Wang,Meng Sun,Chunxuan Shao,Lisa Schlicker, Yue Zhuo,Yassin Harim,Tianping Peng,Weili Tian,Nadja Stöffler,Martin Schneider,Dominic Helm, Youjun Chu,
npj Precision Oncologyno. 1 (2024): 1-21
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn