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Martin Weigert, PhD, is internationally recognized for determining the chain-terminating codons and for his contributions toward understanding autoimmunity and tolerance. His laboratory established two of the most important mouse models of tolerance used by more than 100 laboratories worldwide. For his co-discovery of receptor editing, a fundamental mechanism of B cell tolerance, he was elected to the National Academy of Sciences. He has also made important contributions to understanding mechanisms of directed DNA mutation and how these mechanisms contribute to making antibodies that cause disease.
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