基本信息
浏览量:181
职业迁徙
个人简介
We use both human and mouse cells in vitro and models of atherosclerosis with genetic manipulation to study the role of specific gene products or cells in atherosclerosis. In particular, we have developed unique cell-type ablation systems to analyse the role of specific cells in vivo. Recent work has focussed on the protective mechanisms that ensure survival in VSMCs, and their defects in disease as well as the triggers for VSMC apoptosis and cell senescence. We have also identified novel mechanisms of regulating cell death receptors in vascular cells and how cell: cell interactions govern cell death.
Our clinical studies have used radiofrequency (virtual histology) intravascular ultrasound and computed tomography to determine the types and composition of plaques that determine patient presentation and future events, and are refining these techniques to examine vulnerable plaque characteristics. Our recent work with engineering has examined the mechanical properties of vulnerable plaques, and whether they predict plaque rupture.
Our clinical studies have used radiofrequency (virtual histology) intravascular ultrasound and computed tomography to determine the types and composition of plaques that determine patient presentation and future events, and are refining these techniques to examine vulnerable plaque characteristics. Our recent work with engineering has examined the mechanical properties of vulnerable plaques, and whether they predict plaque rupture.
研究兴趣
论文共 401 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Christopher Wall,Jonathan Weir-McCall, Katharine Tweed, Stephen P Hoole,Deepa Gopalan,Yuan Huang,Andrej Corovic,Marta Peverelli,Damini Dey,Martin R Bennett,James H F Rudd,Anna Kydd,
Laura C. Burzynski, Alejandra Morales-Maldonado,Amanda Rodgers,Lauren A. Kitt,Melanie Humphry,Nichola Figg,Martin R. Bennett,Murray C. H. Clarke
CARDIOVASCULAR RESEARCHno. 1 (2024): 121-121
Christopher Wall,Jonathan Weir-McCall, Katharine Tweed, Stephen P. Hoole,Deepa Gopalan,Yuan Huang,Andrej Corovic,Marta Peverelli,Damini Dey,Martin R. Bennett,James H. F. Rudd,Anna Kydd,
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING (2024)
Laura C. Burzynski, Alejandra Morales-Maldonado, Amanda Rodgers,Lauren A. Kitt,Melanie Humphry,Nichola Figg,Martin R. Bennett,Murray C. H. Clarke
Cardiovascular researchno. 12 (2023): 2179-2189
Christopher Wall,Jonathan Weir-McCall, Katharine Tweed, Stephen P. Hoole,Deepa Gopalan,Yuan Huang,Andrej Corovic,Marta Peverelli,Damini Dey,Martin R. Bennett, James H. F. Rudd,Anna Kydd,
HEARTno. SUPPL_4 (2023): A2-A2
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn