Jacobson Matthew P - Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California, United States of America ; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, California, United States of America.

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论文共 266 篇作者统计合作学者相似作者

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Mutations in α-synuclein, TDP-43 and tau prolong protein half-life through diminished degradation by lysosomal proteases

Paul J Sampognaro,Shruti Arya,Giselle M Knudsen, Emma L Gunderson,Angelica Sandoval-Perez, Molly Hodul, Katherine Bowles,Charles S Craik,Matthew P Jacobson,Aimee W Kao

Molecular neurodegenerationno. 1 (2023): 29-22

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Assessing the Activation of Tyrosine Kinase KIT through Free Energy Calculations

Angélica Sandoval-Pérez, Beth Apsel Winger,Matthew P Jacobson

J Chem Theory Comput（2022）

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Dissecting the effects of GTPase and kinase domain mutations on LRRK2 endosomal localization and activity

Capria Rinaldi,Christopher S. Waters,Karl Kumbier, Lee Rao,R. Jeremy Nichols,Matthew P. Jacobson,Lani F. Wu,Steven J. Altschuler

biorxiv（2022）

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Structure-based discovery of nonopioid analgesics acting through the α 2A -adrenergic receptor

Elissa A Fink,Jun Xu,Harald Hübner,Joao M Braz,Philipp Seemann,Charlotte Avet,Veronica Craik,Dorothee Weikert,Maximilian F Schmidt,Chase M Webb, Nataliya A Tolmachova,Yurii S Moroz,

Science（2022）

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Cysteine Oxidation in Proteins: Structure, Biophysics, and Simulation

Diego Garrido Ruiz,Angelica Sandoval-Perez, Amith Vikram Rangarajan, Emma L Gunderson,Matthew P Jacobson

Biochemistry（2022）

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A scalable screening platform for phenotypic subtyping of ALS patient-derived fibroblasts

Karl Kumbier,Maike Roth,Zizhen Li,Julia Lazzari-Dean, Christopher Waters, Ping Huang,Vlad Korobeynikov, New York Genom Center Consortium,Hemali Phatnani,Neil Schneider,Matt Jacobson, Lani Wu,

biorxiv（2022）

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Signal peptide mimicry primes Sec61 for client-selective inhibition

Shahid Rehan,Dale Tranter,Phillip P. Sharp,Eric Lowe, Janet L. Anderl,Tony Muchamuel,Vahid Abrishami,Suvi Kuivanen, Nicole Wenzell, Andy Jennings,Chakrapani Kalyanaraman, Gregory B. Craven,

biorxiv（2022）

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Fighting Plasmodium chloroquine resistance with acetylenic chloroquine analogues

Wilian A. Cortopassi,Emma Gunderson,Yasmin Annunciato, Antony.E.S. Silva, Amália dos Santos Ferreira,Carolina Bioni Garcia Teles,Andre S. Pimentel, Roopa Ramamoorthi,Marcos Gazarini,Mario R. Meneghetti,Rafael.V.C. Guido,Dhelio B. Pereira,

International Journal for Parasitology: Drugs and Drug Resistance（2022）

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Modulating environmental signals to reveal mechanisms and vulnerabilities of cancer persisters

Xiaoxiao Sun,Jake M Bieber,Heinz Hammerlindl,Robert J Chalkley,Kathy H Li,Alma L Burlingame,Matthew P Jacobson,Lani F Wu,Steven J Altschuler

SCIENCE ADVANCES（2022）

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Specificity of the Lysosomal Proteases in the Degradation of.-synuclein, Tau, and TDP43: Implications for Neurodegenerative Disease

Paul J. Sampognaro,Shruti Arya,Giselle M. Knudsen, Emma L. Gunderson,Angelica Sandoval-Perez,Charles S. Craik,Matthew P. Jacobson,Aimee W. Kao

ANNALS OF NEUROLOGY（2022）

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