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The Zeng laboratory is focused on studying the role of the gut microbiome and maternal-fetal/neonatal immune crosstalk in the development of neonatal or pediatric inflammatory diseases, such as preterm birth, necrotizing enterocolitis, food allergies, asthma, and cancer. Ongoing studies in our laboratory involve in vitro cell biology, microbiology, and immunology assays, disease models in gnotobiotic mice or genetic knockout mice, and examination of clinical samples from newborns and children. Our studies are aimed to identify gut bacteria, bacterial factors or dietary factors that could be potential therapeutic candidates to facilitate appropriate immune responses in early life, with the overarching goal to develop gut microbiome-based preventive approaches to lower the incidence of diseases that are partly attributable to dysregulated immune cell education in early life.
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论文共 21 篇作者统计合作学者相似作者
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Frontiers in immunology (2024): 1417060-1417060
Katherine Z. Sanidad,Stephanie L. Rager, Hannah C. Carrow,Aparna Ananthanarayanan,Ryann Callaghan, Lucy R. Hart,Tingting Li, Purnima Ravisankar,Julia A. Brown,Mohammed Amir, Jenny C. Jin, Alexandria Rose Savage,
SCIENCE IMMUNOLOGYno. 93 (2024): eadj4775-eadj4775
Elsevier eBookspp.181-209, (2023)
Microorganismsno. 3 (2023)
Shui Yu,Melody Y. Zeng
IMMUNITYno. 12 (2023): 2674-2676
Julia A. Brown,Hannah Carrow, Jenny C. Jin,Aparna Ananthanarayanan,Katherine Z. Sanidad, Elizabeth L. Johnson,Jeffrey M. Perlman,Stefan Worgall,Melody Y. Zeng
JOURNAL OF IMMUNOLOGYno. 1 (2022)
Katherine Z. Sanidad,Mohammed Amir,Aparna Ananthanarayanan, Anvita Singaraju, Nicholas B. Shiland,Hanna S. Hong,Nobuhiko Kamada,Naohiro Inohara,Gabriel Nunez,Melody Y. Zeng
SCIENCE IMMUNOLOGYno. 72 (2022)
JOURNAL OF IMMUNOLOGYno. 1 (2022)
Katherine Z. Sanidad,Stephanie L. Rager,Aparna Ananthanarayanan, Ryann Callaghan,Tingting Li, Jenny C. Jin,Mohammed Amir, Ryan Luo, Randi Silver,David Artis,Chun-Jun Guo,Jan Krumsiek,
JOURNAL OF IMMUNOLOGYno. 1 (2022): 59.02-59.02
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