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My lab studies the function of Hedgehog proteins and other extracellular signals in morphogenesis (pattern formation) and in injury repair and regeneration (pattern maintenance). We study how the distribution of such signals is regulated in tissues, how cells perceive and respond to distinct concentrations of signals, and how such signaling pathways arose in evolution. We also study the normal roles of such signals in stem-cell physiology and their abnormal roles in the formation and expansion of cancer stem cells.
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论文共 217 篇作者统计合作学者相似作者
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Lili He, Justine Esther Sato, Praveen Sundar, Tannaz Azimi,Philip Arden Beachy,Laurent Adonis Bekale, Jon-Paul Pepper
International Journal of Biological Macromoleculespp.131747, (2024)
Youngtae Jeong, Ngoc T. Hoang,Alexander Lovejoy, Henning Stehr,Aaron M. Newman,Andrew J. Gentles, William Kong, Diana Truong, Shanique Martin,Aadel Chaudhuri,Diane Heiser,Li Zhou,
crossref(2023)
NEUROUROLOGY AND URODYNAMICS (2023): S11-S13
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CHEMICAL SENSES (2022)
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Shaheen S. Sikandar,Gunsagar S. Gulati,Jane Antony,Isobel J. Fetter,Angera H. Kuo,William Hai Dang Ho, Veronica Haro-Acosta,Soumyashree Das,Chloé B. Steen, Thiago A. Pereira,Dalong Qian,Philip A. Beachy,
Science Advancesno. 45 (2022)
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Science Advancesno. 45 (2022): eabm3548-eabm3548
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