Phillip Popovich
教授
Department of Neuroscience
College of Medicine, The Ohio State University;Belford Center for Spinal Cord Injury, The Ohio State University;Center for Brain and Spinal Cord Repair, The Ohio State University;Institute for Behavioral Medicine Research, The Ohio State University
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个人简介
An often-overlooked feature of a traumatic spinal cord injury (SCI) is the permanent damage cause to the autonomic nervous system (ANS). Many autonomic neurons, including all that comprise the sympathetic branch of the ANS, are located in the spinal cord. After a SCI, profound dysautonomia develops, wreaking havoc on all organ systems, of which the immune system is arguably the most important. Indeed, insufficient or excessive immune responses cause disease and impair healing. All current projects in the Popovich lab are driven by the overall hypothesis that after SCI, an aberrant autonomic anti-inflammatory reflex develops that breaks immune homeostasis which in turn causes or contributes to various pathological sequelae including gastrointestinal dysfunction, systemic infection and deficits in tissue repair (within and outside the spinal cord).
研究兴趣
论文共 284 篇作者统计合作学者相似作者
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EUROPEAN JOURNAL OF IMMUNOLOGYno. 1 (2024): e2250274-e2250274
Jaclyn T Eisdorfer, Josh Thackray,Thomas Theis,Ana Vivinetto,Matthew T Ricci,Sherry Lin, Olisemeka Oputa, Alana M Martinez, Hannah D Nacht, Monica Tschang, Malaika Mahmood,Ashley Tucker,
biorxiv(2024)
Jessica N Wilson,Kristina A Kigerl,Michael D Sunshine,Chase E Taylor,Sydney L Speed, Breanna C Rose,Chris M Calulot,Brittany E Dong,Tara R Hawkinson,Harrison A Clarke,Adam D Bachstetter,Christopher M Waters,
bioRxiv (Cold Spring Harbor Laboratory) (2023)
Jan M. Schwab,Carmen Haider,Marcel A. Kopp,Tobias Zrzavy, Verena Endmayr,Gerda Ricken,Helmut Kubista,Thomas Haider,Thomas Liebscher, Tom Luebstorf,Christian Blex, Leonarda Serdani-Neuhaus,
NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATIONno. 3 (2023): e200099-e200099
Markus E. Harrigan, Angela R. Filous, Christopher P. Vadala,Amy Webb, Maciej Pietrzak,Zarife Sahenk, Harald Pruss, Peter J. Reiser,Phillip G. Popovich, W. David Arnold,Jan M. Schwab
SCIENCE TRANSLATIONAL MEDICINEno. 727 (2023): eadh2156-eadh2156
Cellular, Molecular, Physiological, and Behavioral Aspects of Spinal Cord Injurypp.435-444, (2022)
SSRN Electronic Journal (2022)
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