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I have the capability, training, and motivation necessary to successfully carry out the proposed research project. I have a broad background in protein biochemistry, with specific training and expertise in the field of de-ubiquitination including molecular biology, enzymology, and cell biology. My research includes the study of mutational effect on BRCA1 associated protein 1 (BAP1) function. As a first PhD student of Dr. Tushar K. Maiti, Professor at Regional Center for Biotechnology, Faridabad, India, I got a chance to work on various DUBs like BAP1, UCHL1, UCHL3, UCHL5, OTUB1 and CYLD. I laid the groundwork for the proposed research by standardizing effective measures for protein purification, enzymatic assays, protein-protein interaction, cellular localization and protein aggregation studies. In addition, I successfully administered the other projects collaborated with my lab members and a group in THSTI, Faridabad and produced a number of peer-reviewed publications. As a result of these previous experiences, I am aware of the importance of the BAP1 gene and its wide spread involvement in disease like cancer thus, I got my first postdoctoral researcher position in Dr. Mohamed Abdel-Rahman's lab at Ophthalmology department, Ohio State University. My PhD work was majorly at protein and cell culture level but working with Dr. Mohamed Abdel-Rahman who has expertise in human genetics, access to small animal facility and patient samples helped me to expand my expertise and enter into the clinical setup. Currently, I am working as research associate III in Dr. Smita Patel's lab at department of Biochemistry and Molecular Biology, RWJMS Rutgers University. My current project is focused on understanding the activation of Innate immune response by RNA binding proteins.
Research Interests
Papers共 12 篇Author StatisticsCo-AuthorSimilar Experts
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Nucleic acids researchno. 15 (2023): 8102-8114
Roshan Kumar,Sanjay Kumar,Pranita Hanpude,Abhishek Kumar Singh,Tanu Johari, Sushanta Majumder,Tushar Kanti Maiti
Pawan Kumar,Satyabrata Bag,Tarini Shankar Ghosh,Prasanta Dey,Mayanka Dayal,Bipasa Saha,Jyoti Verma,Archana Pant,Shruti Saxena,Anbumani Desigamani,Preety Rana,Dhirendra Kumar,Naresh C. Sharma,Pranita Hanpude,Tushar K. Maiti,Asish K. Mukhopadhyay,Rupak K. Bhadra,G. Balakrish Nair,Thandavarayan Ramamurthy,Bhabatosh Das
Scientific Reportsno. 1 (2017)
semanticscholar(2017)
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#Papers: 12
#Citation: 311
H-Index: 8
G-Index: 12
Sociability: 4
Diversity: 2
Activity: 2
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