基本信息
浏览量:102
职业迁徙
个人简介
INTERESTS
Bioinformatics; Cancer Genomics; Isoform-level Gene Regulation; Epigenetics; Alternative Promoters and Alternative Splicing.
RESEARCH
Hypothesis: The central hypothesis of his laboratory research is that the isoform-level gene products “transcript variants” and “protein isoforms” are the basic functional units in the mammalian cell, and accordingly, the informatics platforms – ranging from basic molecular biology data management systems to the biomarker and therapeutic drug target discovery for precision medicine – should adapt “gene isoform centric” rather than “gene centric” approaches.
Dr Davuluri is a leader in bioinformatics and data science research. He has more than 20 years of progressive working experience in the areas of bioinformatics and computational genomics; a strong background in statistics and computer science; and synergistic expertise in statistical pattern recognition, machine learning, genomics and bioinformatics. He has served as PI of several multi-investigator and multi-site projects. His lab currently focuses on developing machine learning algorithms and informatics solutions for problems in isoform-level gene regulation and precision-medicine. The overarching goal of the lab is to translate data from high dimensional (-omic) platforms (e.g., NextGen sequencing) to derive experimentally interpretable and testable discovery models towards genomics-based decision support systems. His group is developing bioassays that can rapidly identify biomarkers from human tissue and blood samples. Towards these goals, his group applies a combination of state-of-the-art statistically rigorous data-mining methods and high-throughput experimental procedures in a systems biology setting.
Bioinformatics; Cancer Genomics; Isoform-level Gene Regulation; Epigenetics; Alternative Promoters and Alternative Splicing.
RESEARCH
Hypothesis: The central hypothesis of his laboratory research is that the isoform-level gene products “transcript variants” and “protein isoforms” are the basic functional units in the mammalian cell, and accordingly, the informatics platforms – ranging from basic molecular biology data management systems to the biomarker and therapeutic drug target discovery for precision medicine – should adapt “gene isoform centric” rather than “gene centric” approaches.
Dr Davuluri is a leader in bioinformatics and data science research. He has more than 20 years of progressive working experience in the areas of bioinformatics and computational genomics; a strong background in statistics and computer science; and synergistic expertise in statistical pattern recognition, machine learning, genomics and bioinformatics. He has served as PI of several multi-investigator and multi-site projects. His lab currently focuses on developing machine learning algorithms and informatics solutions for problems in isoform-level gene regulation and precision-medicine. The overarching goal of the lab is to translate data from high dimensional (-omic) platforms (e.g., NextGen sequencing) to derive experimentally interpretable and testable discovery models towards genomics-based decision support systems. His group is developing bioassays that can rapidly identify biomarkers from human tissue and blood samples. Towards these goals, his group applies a combination of state-of-the-art statistically rigorous data-mining methods and high-throughput experimental procedures in a systems biology setting.
研究兴趣
论文共 211 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
ArXiv (2024)
引用0浏览0WOSEI引用
0
0
Alice M. Walsh, Gurpreet S. Kapoor,Janine M. Buonato,Lijoy K. Mathew,Yingtao Bi,Ramana V. Davuluri,Maria Martinez-Lage,M. Celeste Simon, Donald M. O'Rourke,Matthew J. Lazzara
crossref(2023)
Milena S. Nicoloso,Hao Sun,Riccardo Spizzo,Hyunsoo Kim,Priyankara Wickramasinghe,Masayoshi Shimizu,Sylwia E. Wojcik, Jana Ferdin,Tanja Kunej,Lianchun Xiao,Siranoush Manoukian, Giorgio Secreto,
crossref(2023)
crossref(2023)
ICLR 2024 (2023)
crossref(2023)
Kamila Bedelbaeva, Benjamin Cameron, John Latella, Azamat Aslanukov, Dmitri Gourevitch,Ramana Davuluri,Ellen Heber-Katz
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2023): 1101480-1101480
Milena S. Nicoloso,Hao Sun,Riccardo Spizzo,Hyunsoo Kim,Priyankara Wickramasinghe,Masayoshi Shimizu,Sylwia E. Wojcik, Jana Ferdin,Tanja Kunej,Lianchun Xiao,Siranoush Manoukian, Giorgio Secreto,
crossref(2023)
crossref(2023)
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn