Software testing is an expensive, yet imperfect process. Software systems can be large and exhaustive testing is usually not feasible. Products released with inadequate testing can cause bodily harm, result in large economic losses, and affect the quality of day-to-day life. My primary research goal is to develop and examine new software testing techniques that may help testers to more effectively identify software defects. Software testers often intuitively test for defects that they anticipate while less foreseen defects are overlooked. My research applies combinatorial testing strategies that may offset some degree of human bias.