基本信息
浏览量:136
职业迁徙
个人简介
Dr. Keep's primary interests focus on the blood-brain and blood-CSF barriers (the tissue interfaces between the brain and blood) and on stroke. In particular, he has interest in how pathological conditions affect the blood-brain barriers, how the barriers can be protected by techniques such as preconditioning, the normal physiological functions of the barrier tissues and drug transport between blood and brain. These processes are examined in vivo (using rodent models of disease) and using in vitro models of the blood-brain and blood-CSF barriers. In relation to stroke, the Keep Lab investigates the mechanisms of brain injury that follows hemorrhagic and ischemic stroke. Using rodent models of intracerebral hemorrhage, they focus on the roles of thrombin, iron, complement and inflammation in inducing brain injury. In ischemic stroke, they focus on the roles of thrombin, endothelial injury and inflammation in brain injury. Lastly, they examine the effects of novel preconditioning stimuli on both hemorrhagic and ischemic brain injury.
研究兴趣
论文共 511 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Circulation researchno. 6 (2024): 727-747
Proceedings of the National Academy of Sciences of the United States of Americano. 11 (2024): e2400272121-e2400272121
Fluids and Barriers of the CNSno. 1 (2024): 1-15
Momodou G. Bah, Dowlati Ehsan, Max Fleigner,Sravanthi Koduri,Aditya Pandey,Leanne Y. Lin,Thomas L. Chenevert, Jonathan Troost,Guohua Xi,Richard Keep,Neeraj Chaudhary
Neuroimaging Clinics of North Americano. 2 (2024): 215-224
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolismno. 9 (2023): 1475-1489
Experimental neurology (2023): 114523-114523
Neurobiology of disease (2023): 106159-106159
Journal of neurosurgerypp.1-11, (2023)
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn