基本信息
views: 10
Career Trajectory
Bio
Research Interests
Nuclear receptor PPAR in health and diseases
Phytochemicals as therapeutic targets of metabolic diseases
Transgenic animals for disease models
Representative Publications
Ko JK, Lee SST, Martin H: Phytochemicals as modulators of PPARs and RXRs. PPAR Res 2010, 2010:1-2.
Zhao Q, Chan YW, Lee SST, Cheung WT: One-step expression and purification of single-chain variable antibody fragment using an improved hexahistidine tag phagemid vector. Protein Expr Purif 2009,68:190-195.
Sun Y, Ng L, Lam W, Lo CKC, Chan PT, Yuen YL, Wong PF, Tsang DSC, Cheung WT, Lee SST: Identification and characterization of a novel mouse peroxisome proliferator-activated receptor α-regulated and starvation-induced gene, Ppsig. Int J Biochem Cell Biol 2008, 40:1775-1791.
Avasarala S, Yang L, Sun Y, Leung WC, Chan WY, Cheung WT, Lee SST: A temporal study on the histological, biochemical and molecular responses of CCl4-induced hepatotoxicity in Cyp2e1-null mice.Toxicology 2006,228:310-322.
Lee SST, Chan WY, Lo CKC, Wan CC, Tsang SC, Cheung WT: Requirement of PPARα in maintaining phospholipid and triacylglycerol homeostasis during energy deprivation.J Lipid Res 2004,45:2025-2037.
Lee SST, Tian L, Lee WS, Cheung WT: Application of fluorescent differential display and peroxisome proliferator-activated receptor (PPAR)α-null mice to analyze PPAR target genes.Methods Enzymol 2002, 357:214-240.
Peters JM, Lee SST, Li W, Ward JM, Gavrilova O, Everett C, Reitman ML, Hudson LD, Gonzalez FJ: Growth, adipose, brain and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor β (d). Mol Cell Biol 2000,20:5119-5128.
Wong FWY, Chan WY, Lee SST: Resistance to carbon tetrachloride-induced hepatotoxicity in mice which lack CYP2E1 expression.Toxicol Appl Pharmacol 1998, 153:109-118.
Lee SST, Buters JTM, Pineau T, Fernandez-Salguero PM, Gonzalez FJ: Role of CYP2E1 in the hepatotoxicity of acetaminophen. J. Biol Chem 1996,271:12063-12067.
Lee SST, Pineau T, Drago J, Lee EJ, Owens JW, Kroetz DL, Fernandez-Salguero PM, Westphal H, Gonzalez FJ: Targeted disruption of the alpha-isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators.Mol Cell Biol 1995, 15:3012-3022.
Research Interests
Papers共 36 篇Author StatisticsCo-AuthorSimilar Experts
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Arteriosclerosis, Thrombosis, and Vascular Biologyno. 4 (2014): 830-836
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Author Statistics
#Papers: 36
#Citation: 2768
H-Index: 21
G-Index: 35
Sociability: 5
Diversity: 3
Activity: 2
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