基本信息
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Career Trajectory
Bio
My research focus in the metabolomics research is at the comprehensive analysis of all metabolites in a studied biological system that can describe metabolic changes caused by disease, environmental, nutritional, or genetic factors in an organism. For this, the goal in my research has been the development of efficient, high-throughput methodologies for profiling of the biological samples, based on both more conventional chromatographic methods as well as in comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry, ultra high performance liquid chromatography combined with various mass spectrometers. We have been developing both non-targeted profiling methods in discovery studies, as well as for targeted analysis of specific compounds, with the goal for as comprehensive coverage of the metabolome as possible. Here, the major goal is the development of more reliable and sensitive methodologies, particularly for comprehensive profiling of complex samples. Identification of unknown compounds with the mass spectrometric tools is the main challenge in the research. For this, development of software tools for the treatment of MS data has been a key issue as manual identification of hundreds or even thousands of unknown compounds in large sample series is not a viable option.
Research Interests
Papers共 310 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
The Science of the total environment (2024): 176004-176004
SCIENCE OF THE TOTAL ENVIRONMENT (2024): 167307-167307
Heidi Isokaanta, Lucas Pinto da Silva,Naama Karu,Teemu Kallonen,Anna-Katariina Aatsinki, Thomas Hankemeier,Leyla Schimmel,Edgar Diaz,Tuulia Hyotylainen,Pieter C. Dorrestein,Rob Knight,Matej Oresic,Rima Kaddurah-Daouk,Alex M. Dickens,Santosh Lamichhane
Analytical chemistryno. 22 (2024): 8893-8904
Environment international (2024): 108820-108820
ENVIRONMENTAL MICROBIOLOGYno. 1 (2024)
Metabolitesno. 6 (2024)
ENVIRONMENT INTERNATIONAL (2024)
Food hydrocolloids (2024): 109306-109306
Cellno. 8 (2024): 1853-1873.e15
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Author Statistics
#Papers: 310
#Citation: 14592
H-Index: 57
G-Index: 115
Sociability: 7
Diversity: 0
Activity: 3
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