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个人简介
Dr. Greten is a physician-scientist who uses his medical expertise in Gastroenterology, Hepatology and Medical Oncology along with his research expertise in tumor immunology to develop novel treatments for patients with cancer. He heads a research team to study the tumor microenvironment in the liver in the context of Hepatocellular Carcinoma, Cholangiocarcinoma, and liver metastasis and studies how exogenous factors such as diet and the gut microbiome may affect immune responses in the liver. He also directs the GI Medical Oncology clinical team, that conducts clinical trials in patients with GI cancers. He and his team cover the entire research spectrum from basic tumor immunology and use of complex murine cancer models to the development and evaluation of new immunotherapies (including CAR T cells) for patients with gastrointestinal cancers. He conducts investigator-initiated first-in-human trials, phase I and II trials and has been one of the first investigators to test immune checkpoint inhibitors in patients with Hepatocellular carcinoma and Cholangiocarcinoma either alone or in combination with locoregional therapies.
研究兴趣
论文共 434 篇作者统计合作学者相似作者
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JHEP REPORTSno. 1 (2024): 100959-100959
CANCER MEDICINEno. 1 (2024): n/a-n/a
Cecilia Monge,Changqing Xie, Yuta Myojin,Kelley L. Coffman-D'Annibale,Donna Hrones, Gagandeep Brar, Sophie Wang, Anuradha Budhu, William D. Figg, Maggie Cam, Richard Finney, Elliot B. Levy,
CANCER MEDICINEno. 3 (2024): e6912-e6912
Sylvan C. Baca,Ji-Heui Seo,Matthew P. Davidsohn, Brad Fortunato,Karl Semaan, Shahabbedin Sotudian,Gitanjali Lakshminarayanan,Miklos Diossy,Xintao Qiu,Talal El Zarif, Hunter Savignano, John Canniff,
Nature Medicineno. 3 (2024): 907-907
Rajiv S. Trehan, Marlaine Soliman, Xin Wang,Patrick Huang,Noemi Kedei, Xiao Bin Zhu,Matthias Seifert,Mohamed-Reda Benmebarek, Amran Nur,Firouzeh Korangy,Chi Ma,Tim F. Greten
Cancer Researchno. 6_Supplement (2024): 3970-3970
Cancer Researchno. 6_Supplement (2024): 5335-5335
Cancer Researchno. 6_Supplement (2024): 2694-2694
JOURNAL FOR IMMUNOTHERAPY OF CANCERno. 1 (2024)
Hepatology (Baltimore, Md.) (2024)
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