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To understand how the fundamental processes of localised translation and egg activation are achieved, we use Drosophila as a model system since imaging, biochemistry and genetic approaches can be readily combined to examine molecular mechanisms. Drosophila research has identified thousands of genes with human homologues and has provided key insights into developmental pathways, oncology, neurobiology and immunology. Our use of the egg chamber and early embryo has the added experimental benefits of: being an in vivo developing system; allowing for a controllable switch at egg activation; ease of physical manipulation; and providing ample material for experimentation.
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论文共 64 篇作者统计合作学者相似作者
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Nature Communicationsno. 1 (2024): 1-13
PLoS geneticsno. 1 (2024): e1011111-e1011111
Genesno. 9 (2023): 1675-1675
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature (2022)
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature (2022)
bioRxiv (Cold Spring Harbor Laboratory) (2022)
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