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The heart is very dependent on energy to perform its function as a pump and consumes more energy than any other organ in the body. We know that in the clinical syndrome of heart failure (where the heart does not pump enough blood around the body), there is a deficit in energy supply which seems to be progressive with the condition and is particularly worse when the heart is asked to perform exercise. We are learning more about how and why this occurs and it seems that a switch in the 'fuel' that the heart uses to produce this energy plays a major role.
Our group uses magnetic resonance spectroscopy (MRS) sequences to see the amount of energy inside living peoples' hearts and the sorts of fuel the heart is using. My research looks into how using different approaches to alter the fuel the heart uses can improve the amount of energy available to it, paving the way for new treatments.
Our group uses magnetic resonance spectroscopy (MRS) sequences to see the amount of energy inside living peoples' hearts and the sorts of fuel the heart is using. My research looks into how using different approaches to alter the fuel the heart uses can improve the amount of energy available to it, paving the way for new treatments.
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European heart journal. Imaging methods and practiceno. 2 (2023): qyad035-qyad035
Circulation (2021)
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