Characterization of progressive HIV-associated tuberculosis using 2-deoxy-2-[ 18 F]fluoro- D -glucose positron emission and computed tomography

Hanif Esmail,Rachel P Lai,Maia Lesosky,Katalin A Wilkinson,Christine M Graham,Anna K Coussens,Tolu Oni,James M Warwick, Qonita Said-Hartley,Coenraad F Koegelenberg,Gerhard Walzl,JoAnne L Flynn,Douglas B Young,Clifton E Barry III,Anne O'Garra,Robert J Wilkinson

Nature medicine（2016）

引用 153|浏览8

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摘要

By using combined positron emission and computed tomography (PET–CT), Esmail et al. show that some patients with latent tuberculosis have signs of subclinical, active disease in the lungs and a greater likelihood of progression, suggesting a spectrum of disease rather than discrete latent and active disease states.

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关键词

Tuberculosis,Infection,HIV infections,Translational research

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