C13orf31 (FAMIN) is a central regulator of immunometabolic function

Nature Immunology（2016）

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摘要

Variants of the human gene C13orf31 ( LACC1 ) are associated with various disease risks. Kaser and colleagues identify a role for the protein encoded (called ‘FAMIN’) in regulating macrophage fatty-acid oxidation and lipogenesis.

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Cell biology,Immunology

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