Advanced Glycation Endproducts, Dityrosine and Arginine Transporter Dysfunction in Autism - a Source of Biomarkers for Clinical Diagnosis
Molecular autism(2018)
摘要
Clinical chemistry tests for autism spectrum disorder (ASD) are currently unavailable. The aim of this study was to explore the diagnostic utility of proteotoxic biomarkers in plasma and urine, plasma protein glycation, oxidation, and nitration adducts, and related glycated, oxidized, and nitrated amino acids (free adducts), for the clinical diagnosis of ASD.
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关键词
Autism spectrum disorder (ASD),Advanced glycation endproducts (AGEs),Oxidative stress,Amino acid metabolome,Machine learning
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