Genome-wide Scan Identifies Role for AOX1 in Prostate Cancer Survival.

Weiqiang Li,Mridu Middha,Mesude Bicak,Daniel D Sjoberg,Emily Vertosick,Anders Dahlin,Christel Häggström,Göran Hallmans,Ann-Charlotte Rönn,Pär Stattin,Olle Melander,David Ulmert,Hans Lilja,Robert J Klein

European Urology（2018）

引用 44|浏览20

暂无评分

摘要

We performed genome-wide association studies and found single nucleotide polymorphisms (SNPs) at seven independent loci associated with prostate-cancer-specific survival time. Two SNPs replicated in an independent cohort. The SNP rs73055188 at AOX1 is associated with AOX1 gene expression level, which is correlated with biochemical recurrence.

查看译文

关键词

AOX1,Expression quantitative trait locus,Genome-wide association study,Prostate cancer,Survival analysis

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要