EXPLORER-HCM: Phase 3 Randomized, Multi-Center, Double-Blind, Placebo-Controlled Study to Evaluate Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Iacopo Olivotto,Carolyn Ho,Daniel Jacoby,Steven Lester,Matthew Roe,Andrew Wang, Jean-Francois Tamby,Joseph Lambing,June Lee,David Zhang,Amy Sehnert, Stephan Heitner

Circulation（2018）

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摘要

Introduction: Hypertrophic cardiomyopathy, carries substantial lifelong morbidity, often associated with dynamic left ventricular outflow tract (LVOT) obstruction (oHCM). Since its original descrip...

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