Population-scale proteome variation in 1 human induced pluripotent stem cells 2 3

3 Bogdan A Mirauta1,*, Daniel D Seaton1,*, Dalila Bensaddek2,*, Alejandro Brenes2, 4 Marc J Bonder1, Helena Kilpinen1,⟊, HipSci Consortium, Oliver Stegle1,3,4#, Angus I 5 Lamond2,# 6 7 1 European Molecular Biology Laboratory, European Bioinformatics Institute, 8 Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK 9 2 Centre for Gene Regulation & Expression, School of Life Sciences, University of 10 Dundee, Dundee, DD1 5EH, UK 11 3 European Molecular Biology Laboratory, Genome Biology Unit, 69117 Heidelberg, 12 Germany 13 4 Division of Computational Genomics and Systems Genetics, German Cancer 14 Research Center, 69120 Heidelberg, Germany 15 16 * equal contribution 17 # equal contribution 18 ⟊ present address: UCL Great Ormond Street Institute of Child Health, University 19 College London, London WC1N 1EH, UK 20 21 Correspondence to: a.i.lamond@dundee.ac.uk, oliver.stegle@ebi.ac.uk 22 23 24 25 26 27