Dissecting melanocytes to predict melanoma

NATURE CELL BIOLOGY(2021)

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摘要
With advanced high-throughput technologies, scientists can now use transcriptional signatures to study melanocytes as they become cancer. A new study identifies transcriptional programs at single-cell resolution across platforms and species, which enables prediction of melanoma prognosis and response to immune-checkpoint inhibitor therapy.
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关键词
Differentiation,Melanoma,RNA sequencing,Tumour heterogeneity,Life Sciences,general,Cell Biology,Cancer Research,Developmental Biology,Stem Cells
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