MT 3-MMP promotes excitatory synapse formation by promoting Nogo-66 receptor 1 ectodomain shedding 2 3 Abbreviated title : NgR 1 shedding in excitatory synapse formation 4 5

MT3-MMP promotes excitatory synapse formation by promoting Nogo-66 receptor ectodomain shedding Ricardo L. Sanz, Gino B. Ferraro, Johannes Kacervosky, Charleen Salesse, Elizabeth Gowing, Luyang Hua, Isabel Rambaldi, Francois Beaubien, Kenn Holmbeck, J. F. Cloutier, Martin Lévesque, Keith Murai and Alyson E. Fournier Department of Neurology and Neurosurgery, Montréal Neurological Institute, 3801 Rue University, Montréal, Québec, H3A 2B4, Canada Centre for Research in Neuroscience, Department of Neurology and Neurosurgery, The Research Institute of the McGill University Health Centre, Montreal General Hospital, Montréal, Québec, Canada Department of Psychiatry and Neuroscience, Université Laval, CERVO Brain Research Centre, Québec, Québec, G1J2G3, Canada Craniofacial and Skeletal Diseases Branch, NIDCR, National Institutes of Health (NIH), Bethesda, Maryland 20892-4380, USA