Super resolution microscopy analysis reveals increased Orai1 activity in asthma and cystic fibrosis lungs.

Alexandra S Goriounova,Rodney C Gilmore,Joe A Wrennall,Robert Tarran

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society（2023）

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摘要

We found evidence that Orai1 was more active in asthma and CF than normal lungs. These data suggest that Orai1 is a relevant target for reducing pulmonary inflammation.

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关键词

Asthma,Cystic fibrosis,Inflammation,Orai1/STIM1,RNAscope,Super resolution microscopy

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